LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Neratinib | 0.12 | uM | LJP5 | 1 | A17 | 72 | hr | 1694 | 4597 | 11042 | 0.4163 | 0.4464 |
| MCF 10A | Neratinib | 0.12 | uM | LJP5 | 2 | A17 | 72 | hr | 1694 | 4187 | 11099 | 0.3772 | 0.3960 |
| MCF 10A | Neratinib | 0.12 | uM | LJP5 | 3 | A17 | 72 | hr | 1694 | 4330 | 11168 | 0.3877 | 0.4118 |
| MCF 10A | Neratinib | 0.37 | uM | LJP5 | 1 | A16 | 72 | hr | 1694 | 3652 | 11042 | 0.3307 | 0.3284 |
| MCF 10A | Neratinib | 0.37 | uM | LJP5 | 2 | A16 | 72 | hr | 1694 | 3688 | 11099 | 0.3323 | 0.3322 |
| MCF 10A | Neratinib | 0.37 | uM | LJP5 | 3 | A16 | 72 | hr | 1694 | 3334 | 11168 | 0.2985 | 0.2825 |
| MCF 10A | Neratinib | 1.11 | uM | LJP5 | 1 | A15 | 72 | hr | 1694 | 3633 | 11042 | 0.3290 | 0.3259 |
| MCF 10A | Neratinib | 1.11 | uM | LJP5 | 2 | A15 | 72 | hr | 1694 | 3295 | 11099 | 0.2969 | 0.2780 |
| MCF 10A | Neratinib | 1.11 | uM | LJP5 | 3 | A15 | 72 | hr | 1694 | 2845 | 11168 | 0.2547 | 0.2099 |
| MCF 10A | Neratinib | 3.33 | uM | LJP5 | 1 | A14 | 72 | hr | 1694 | 2528 | 11042 | 0.2289 | 0.1595 |
| MCF 10A | Neratinib | 3.33 | uM | LJP5 | 2 | A14 | 72 | hr | 1694 | 2872 | 11099 | 0.2588 | 0.2149 |
| MCF 10A | Neratinib | 3.33 | uM | LJP5 | 3 | A14 | 72 | hr | 1694 | 2624 | 11168 | 0.2350 | 0.1744 |
| MCF 10A | Neratinib | 10 | uM | LJP5 | 1 | A13 | 72 | hr | 1694 | 2389 | 11042 | 0.2164 | 0.1355 |
| MCF 10A | Neratinib | 10 | uM | LJP5 | 2 | A13 | 72 | hr | 1694 | 2673 | 11099 | 0.2408 | 0.1831 |
| MCF 10A | Neratinib | 10 | uM | LJP5 | 3 | A13 | 72 | hr | 1694 | 2327 | 11168 | 0.2084 | 0.1237 |
| MCF 10A | JW-7-24-1 | 0.04 | uM | LJP6 | 1 | B24 | 72 | hr | 1694 | 11432 | 11220 | 1.0188 | 1.0137 |
| MCF 10A | JW-7-24-1 | 0.04 | uM | LJP6 | 2 | B24 | 72 | hr | 1694 | 10750 | 11309 | 0.9505 | 0.9633 |
| MCF 10A | JW-7-24-1 | 0.04 | uM | LJP6 | 3 | B24 | 72 | hr | 1694 | 11329 | 11121 | 1.0187 | 1.0137 |
| MCF 10A | JW-7-24-1 | 0.12 | uM | LJP6 | 1 | B23 | 72 | hr | 1694 | 11553 | 11220 | 1.0296 | 1.0215 |
| MCF 10A | JW-7-24-1 | 0.12 | uM | LJP6 | 2 | B23 | 72 | hr | 1694 | 11941 | 11309 | 1.0559 | 1.0401 |
| MCF 10A | JW-7-24-1 | 0.12 | uM | LJP6 | 3 | B23 | 72 | hr | 1694 | 11415 | 11121 | 1.0264 | 1.0193 |
| MCF 10A | JW-7-24-1 | 0.37 | uM | LJP6 | 1 | B22 | 72 | hr | 1694 | 11565 | 11220 | 1.0307 | 1.0223 |
| MCF 10A | JW-7-24-1 | 0.37 | uM | LJP6 | 2 | B22 | 72 | hr | 1694 | 11534 | 11309 | 1.0199 | 1.0144 |
| MCF 10A | JW-7-24-1 | 0.37 | uM | LJP6 | 3 | B22 | 72 | hr | 1694 | 11553 | 11121 | 1.0388 | 1.0283 |
| MCF 10A | JW-7-24-1 | 1.11 | uM | LJP6 | 1 | B21 | 72 | hr | 1694 | 11538 | 11220 | 1.0283 | 1.0205 |