LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Dactolisib
3.33
uM
LJP5
 1
M14
 72
hr
 765 881 3140 0.2805 0.0717
Hs 578T Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 765 830 3151 0.2634 0.0407
Hs 578T Dactolisib
3.33
uM
LJP5
 3
M14
 72
hr
 765 850 3152 0.2696 0.0529
Hs 578T Dactolisib
10
uM
LJP5
 1
M13
 72
hr
 765 858 3140 0.2732 0.0579
Hs 578T Dactolisib
10
uM
LJP5
 2
M13
 72
hr
 765 936 3151 0.2970 0.1038
Hs 578T Dactolisib
10
uM
LJP5
 3
M13
 72
hr
 765 886 3152 0.2811 0.0745
Hs 578T Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 765 2966 3140 0.9445 0.9447
Hs 578T Alpelisib
0.04
uM
LJP5
 2
N06
 72
hr
 765 3033 3151 0.9624 0.9628
Hs 578T Alpelisib
0.04
uM
LJP5
 3
N06
 72
hr
 765 3043 3152 0.9653 0.9657
Hs 578T Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 765 2916 3140 0.9286 0.9285
Hs 578T Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 765 2879 3151 0.9135 0.9133
Hs 578T Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 765 2859 3152 0.9069 0.9066
Hs 578T Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 765 2531 3140 0.8060 0.7991
Hs 578T Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 765 2704 3151 0.8580 0.8555
Hs 578T Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 765 2747 3152 0.8714 0.8697
Hs 578T Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 765 2524 3140 0.8037 0.7966
Hs 578T Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 765 2631 3151 0.8348 0.8308
Hs 578T Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 765 2560 3152 0.8121 0.8062
Hs 578T Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 765 2286 3140 0.7279 0.7114
Hs 578T Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 765 2469 3151 0.7834 0.7747
Hs 578T Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 765 2472 3152 0.7842 0.7756
Hs 578T Alpelisib
10
uM
LJP5
 1
N01
 72
hr
 765 1778 3140 0.5662 0.5128
Hs 578T Alpelisib
10
uM
LJP5
 2
N01
 72
hr
 765 1774 3151 0.5629 0.5095
Hs 578T Alpelisib
10
uM
LJP5
 3
N01
 72
hr
 765 1719 3152 0.5453 0.4863
Hs 578T GDC-0980
0.04
uM
LJP5
 1
K24
 72
hr
 765 2229 3140 0.7098 0.6903