LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T PIK-93
0.12
uM
LJP5
 3
K17
 72
hr
 765 3191 3152 1.0122 1.0119
Hs 578T PIK-93
0.37
uM
LJP5
 1
K16
 72
hr
 765 3060 3140 0.9744 0.9747
Hs 578T PIK-93
0.37
uM
LJP5
 2
K16
 72
hr
 765 3089 3151 0.9801 0.9804
Hs 578T PIK-93
0.37
uM
LJP5
 3
K16
 72
hr
 765 3218 3152 1.0208 1.0203
Hs 578T PIK-93
1.11
uM
LJP5
 1
K15
 72
hr
 765 2946 3140 0.9381 0.9383
Hs 578T PIK-93
1.11
uM
LJP5
 2
K15
 72
hr
 765 3066 3151 0.9728 0.9732
Hs 578T PIK-93
1.11
uM
LJP5
 3
K15
 72
hr
 765 2900 3152 0.9199 0.9199
Hs 578T PIK-93
3.33
uM
LJP5
 1
K14
 72
hr
 765 1347 3140 0.4289 0.3201
Hs 578T PIK-93
3.33
uM
LJP5
 2
K14
 72
hr
 765 1605 3151 0.5093 0.4373
Hs 578T PIK-93
3.33
uM
LJP5
 3
K14
 72
hr
 765 1611 3152 0.5110 0.4398
Hs 578T PIK-93
10
uM
LJP5
 1
K13
 72
hr
 765 610 3140 0.1943 -0.1052
Hs 578T PIK-93
10
uM
LJP5
 2
K13
 72
hr
 765 761 3151 0.2415 -0.0026
Hs 578T PIK-93
10
uM
LJP5
 3
K13
 72
hr
 765 684 3152 0.2170 -0.0533
Hs 578T Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 765 1137 3140 0.3621 0.2147
Hs 578T Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 765 1127 3151 0.3576 0.2088
Hs 578T Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 765 1079 3152 0.3423 0.1833
Hs 578T Dactolisib
0.12
uM
LJP5
 1
M17
 72
hr
 765 940 3140 0.2993 0.1064
Hs 578T Dactolisib
0.12
uM
LJP5
 2
M17
 72
hr
 765 1021 3151 0.3240 0.1518
Hs 578T Dactolisib
0.12
uM
LJP5
 3
M17
 72
hr
 765 1034 3152 0.3280 0.1589
Hs 578T Dactolisib
0.37
uM
LJP5
 1
M16
 72
hr
 765 811 3140 0.2583 0.0290
Hs 578T Dactolisib
0.37
uM
LJP5
 2
M16
 72
hr
 765 817 3151 0.2592 0.0327
Hs 578T Dactolisib
0.37
uM
LJP5
 3
M16
 72
hr
 765 891 3152 0.2826 0.0775
Hs 578T Dactolisib
1.11
uM
LJP5
 1
M15
 72
hr
 765 781 3140 0.2487 0.0102
Hs 578T Dactolisib
1.11
uM
LJP5
 2
M15
 72
hr
 765 809 3151 0.2567 0.0277
Hs 578T Dactolisib
1.11
uM
LJP5
 3
M15
 72
hr
 765 806 3152 0.2557 0.0259