LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Y39983
3.33
uM
LJP6
 3
P02
 72
hr
 765 2044 3066 0.6667 0.6334
Hs 578T Y39983
10
uM
LJP6
 1
P01
 72
hr
 765 664 3143 0.2112 -0.0671
Hs 578T Y39983
10
uM
LJP6
 2
P01
 72
hr
 765 786 3095 0.2539 0.0135
Hs 578T Y39983
10
uM
LJP6
 3
P01
 72
hr
 765 771 3066 0.2515 0.0039
Hs 578T Nintedanib
0.04
uM
LJP6
 1
H06
 72
hr
 765 2869 3143 0.9126 0.9123
Hs 578T Nintedanib
0.04
uM
LJP6
 2
H06
 72
hr
 765 2775 3095 0.8964 0.8944
Hs 578T Nintedanib
0.04
uM
LJP6
 3
H06
 72
hr
 765 2804 3066 0.9146 0.9128
Hs 578T Nintedanib
0.12
uM
LJP6
 1
H05
 72
hr
 765 2716 3143 0.8639 0.8616
Hs 578T Nintedanib
0.12
uM
LJP6
 2
H05
 72
hr
 765 2692 3095 0.8696 0.8661
Hs 578T Nintedanib
0.12
uM
LJP6
 3
H05
 72
hr
 765 2597 3066 0.8470 0.8409
Hs 578T Nintedanib
0.37
uM
LJP6
 1
H04
 72
hr
 765 2328 3143 0.7405 0.7260
Hs 578T Nintedanib
0.37
uM
LJP6
 2
H04
 72
hr
 765 2246 3095 0.7255 0.7058
Hs 578T Nintedanib
0.37
uM
LJP6
 3
H04
 72
hr
 765 2281 3066 0.7440 0.7254
Hs 578T Nintedanib
1.11
uM
LJP6
 1
H03
 72
hr
 765 2192 3143 0.6973 0.6758
Hs 578T Nintedanib
1.11
uM
LJP6
 2
H03
 72
hr
 765 2218 3095 0.7165 0.6952
Hs 578T Nintedanib
1.11
uM
LJP6
 3
H03
 72
hr
 765 2131 3066 0.6950 0.6678
Hs 578T Nintedanib
3.33
uM
LJP6
 1
H02
 72
hr
 765 1211 3143 0.3852 0.2526
Hs 578T Nintedanib
3.33
uM
LJP6
 2
H02
 72
hr
 765 1734 3095 0.5601 0.5004
Hs 578T Nintedanib
3.33
uM
LJP6
 3
H02
 72
hr
 765 1859 3066 0.6063 0.5579
Hs 578T Nintedanib
10
uM
LJP6
 1
H01
 72
hr
 765 1291 3143 0.4107 0.2926
Hs 578T Nintedanib
10
uM
LJP6
 2
H01
 72
hr
 765 1185 3095 0.3828 0.2423
Hs 578T Nintedanib
10
uM
LJP6
 3
H01
 72
hr
 765 1029 3066 0.3356 0.1595
Hs 578T Foretinib
0.04
uM
LJP5
 1
H12
 72
hr
 765 2849 3140 0.9072 0.9067
Hs 578T Foretinib
0.04
uM
LJP5
 2
H12
 72
hr
 765 2794 3151 0.8865 0.8855
Hs 578T Foretinib
0.04
uM
LJP5
 3
H12
 72
hr
 765 2783 3152 0.8828 0.8816