LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T PLX-4720
0.37
uM
LJP5
 3
K04
 72
hr
 765 3803 3152 1.2064 1.1924
Hs 578T PLX-4720
1.11
uM
LJP5
 1
K03
 72
hr
 765 3634 3140 1.1572 1.1486
Hs 578T PLX-4720
1.11
uM
LJP5
 2
K03
 72
hr
 765 3822 3151 1.2127 1.1980
Hs 578T PLX-4720
1.11
uM
LJP5
 3
K03
 72
hr
 765 3750 3152 1.1896 1.1774
Hs 578T PLX-4720
3.33
uM
LJP5
 1
K02
 72
hr
 765 3170 3140 1.0094 1.0092
Hs 578T PLX-4720
3.33
uM
LJP5
 2
K02
 72
hr
 765 3358 3151 1.0655 1.0631
Hs 578T PLX-4720
3.33
uM
LJP5
 3
K02
 72
hr
 765 3392 3152 1.0760 1.0730
Hs 578T PLX-4720
10
uM
LJP5
 1
K01
 72
hr
 765 2296 3140 0.7311 0.7150
Hs 578T PLX-4720
10
uM
LJP5
 2
K01
 72
hr
 765 2322 3151 0.7368 0.7222
Hs 578T PLX-4720
10
uM
LJP5
 3
K01
 72
hr
 765 2126 3152 0.6744 0.6492
Hs 578T Lapatinib
0.04
uM
LJP6
 1
M24
 72
hr
 765 3144 3143 1.0001 1.0001
Hs 578T Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 765 3037 3095 0.9811 0.9811
Hs 578T Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 765 3123 3066 1.0186 1.0185
Hs 578T Lapatinib
0.12
uM
LJP6
 1
M23
 72
hr
 765 2985 3143 0.9495 0.9498
Hs 578T Lapatinib
0.12
uM
LJP6
 2
M23
 72
hr
 765 3018 3095 0.9749 0.9750
Hs 578T Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 765 3075 3066 1.0029 1.0029
Hs 578T Lapatinib
0.37
uM
LJP6
 1
M22
 72
hr
 765 3018 3143 0.9600 0.9603
Hs 578T Lapatinib
0.37
uM
LJP6
 2
M22
 72
hr
 765 3085 3095 0.9966 0.9966
Hs 578T Lapatinib
0.37
uM
LJP6
 3
M22
 72
hr
 765 3041 3066 0.9919 0.9918
Hs 578T Lapatinib
1.11
uM
LJP6
 1
M21
 72
hr
 765 2974 3143 0.9460 0.9463
Hs 578T Lapatinib
1.11
uM
LJP6
 2
M21
 72
hr
 765 3101 3095 1.0017 1.0017
Hs 578T Lapatinib
1.11
uM
LJP6
 3
M21
 72
hr
 765 3123 3066 1.0186 1.0185
Hs 578T Lapatinib
3.33
uM
LJP6
 1
M20
 72
hr
 765 2979 3143 0.9476 0.9479
Hs 578T Lapatinib
3.33
uM
LJP6
 2
M20
 72
hr
 765 3054 3095 0.9866 0.9866
Hs 578T Lapatinib
3.33
uM
LJP6
 3
M20
 72
hr
 765 3066 3066 1.0000 1.0000