LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Lapatinib
10
uM
LJP6
 1
M19
 72
hr
 765 2345 3143 0.7459 0.7322
Hs 578T Lapatinib
10
uM
LJP6
 2
M19
 72
hr
 765 2156 3095 0.6965 0.6716
Hs 578T Lapatinib
10
uM
LJP6
 3
M19
 72
hr
 765 2129 3066 0.6944 0.6670
Hs 578T Sirolimus
0.04
uM
LJP6
 1
L18
 72
hr
 765 1862 3143 0.5923 0.5469
Hs 578T Sirolimus
0.04
uM
LJP6
 2
L18
 72
hr
 765 1828 3095 0.5905 0.5402
Hs 578T Sirolimus
0.04
uM
LJP6
 3
L18
 72
hr
 765 1806 3066 0.5890 0.5355
Hs 578T Sirolimus
0.12
uM
LJP6
 1
L17
 72
hr
 765 1911 3143 0.6079 0.5667
Hs 578T Sirolimus
0.12
uM
LJP6
 2
L17
 72
hr
 765 1849 3095 0.5973 0.5490
Hs 578T Sirolimus
0.12
uM
LJP6
 3
L17
 72
hr
 765 1938 3066 0.6321 0.5906
Hs 578T Sirolimus
0.37
uM
LJP6
 1
L16
 72
hr
 765 1951 3143 0.6206 0.5827
Hs 578T Sirolimus
0.37
uM
LJP6
 2
L16
 72
hr
 765 1879 3095 0.6070 0.5614
Hs 578T Sirolimus
0.37
uM
LJP6
 3
L16
 72
hr
 765 1883 3066 0.6142 0.5679
Hs 578T Sirolimus
1.11
uM
LJP6
 1
L15
 72
hr
 765 1955 3143 0.6219 0.5843
Hs 578T Sirolimus
1.11
uM
LJP6
 2
L15
 72
hr
 765 1788 3095 0.5776 0.5234
Hs 578T Sirolimus
1.11
uM
LJP6
 3
L15
 72
hr
 765 1828 3066 0.5962 0.5449
Hs 578T Sirolimus
3.33
uM
LJP6
 1
L14
 72
hr
 765 1947 3143 0.6193 0.5811
Hs 578T Sirolimus
3.33
uM
LJP6
 2
L14
 72
hr
 765 1769 3095 0.5715 0.5154
Hs 578T Sirolimus
3.33
uM
LJP6
 3
L14
 72
hr
 765 1839 3066 0.5998 0.5495
Hs 578T Sirolimus
10
uM
LJP6
 1
L13
 72
hr
 765 1779 3143 0.5659 0.5127
Hs 578T Sirolimus
10
uM
LJP6
 2
L13
 72
hr
 765 1750 3095 0.5653 0.5073
Hs 578T Sirolimus
10
uM
LJP6
 3
L13
 72
hr
 765 1808 3066 0.5897 0.5364
Hs 578T ZSTK474
0.04
uM
LJP6
 1
M18
 72
hr
 765 2480 3143 0.7889 0.7804
Hs 578T ZSTK474
0.04
uM
LJP6
 2
M18
 72
hr
 765 2606 3095 0.8418 0.8363
Hs 578T ZSTK474
0.04
uM
LJP6
 3
M18
 72
hr
 765 2382 3066 0.7769 0.7632
Hs 578T ZSTK474
0.12
uM
LJP6
 1
M17
 72
hr
 765 2189 3143 0.6963 0.6747