LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 765 3322 3066 1.0835 1.0817
Hs 578T Imatinib
10
uM
LJP6
 1
N13
 72
hr
 765 3402 3143 1.0821 1.0789
Hs 578T Imatinib
10
uM
LJP6
 2
N13
 72
hr
 765 3391 3095 1.0954 1.0925
Hs 578T Imatinib
10
uM
LJP6
 3
N13
 72
hr
 765 3368 3066 1.0985 1.0961
Hs 578T NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 765 2883 3143 0.9171 0.9168
Hs 578T NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 765 2872 3095 0.9278 0.9270
Hs 578T NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 765 2882 3066 0.9400 0.9391
Hs 578T NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 765 1838 3143 0.5847 0.5371
Hs 578T NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 765 1972 3095 0.6370 0.5992
Hs 578T NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 765 1876 3066 0.6119 0.5650
Hs 578T NVP-TAE684
0.37
uM
LJP6
 1
K16
 72
hr
 765 2136 3143 0.6794 0.6546
Hs 578T NVP-TAE684
0.37
uM
LJP6
 2
K16
 72
hr
 765 2151 3095 0.6949 0.6697
Hs 578T NVP-TAE684
0.37
uM
LJP6
 3
K16
 72
hr
 765 2159 3066 0.7042 0.6787
Hs 578T NVP-TAE684
1.11
uM
LJP6
 1
K15
 72
hr
 765 1578 3143 0.5019 0.4263
Hs 578T NVP-TAE684
1.11
uM
LJP6
 2
K15
 72
hr
 765 1464 3095 0.4729 0.3796
Hs 578T NVP-TAE684
1.11
uM
LJP6
 3
K15
 72
hr
 765 1395 3066 0.4550 0.3498
Hs 578T NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 765 954 3143 0.3035 0.1143
Hs 578T NVP-TAE684
3.33
uM
LJP6
 2
K14
 72
hr
 765 927 3095 0.2995 0.0999
Hs 578T NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 765 792 3066 0.2583 0.0174
Hs 578T NVP-TAE684
10
uM
LJP6
 1
K13
 72
hr
 765 573 3143 0.1823 -0.1322
Hs 578T NVP-TAE684
10
uM
LJP6
 2
K13
 72
hr
 765 586 3095 0.1893 -0.1238
Hs 578T NVP-TAE684
10
uM
LJP6
 3
K13
 72
hr
 765 436 3066 0.1422 -0.2448
Hs 578T CGP60474
0.04
uM
LJP6
 1
G06
 72
hr
 765 296 3143 0.0942 -0.3723
Hs 578T CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 765 361 3095 0.1166 -0.3110
Hs 578T CGP60474
0.04
uM
LJP6
 3
G06
 72
hr
 765 383 3066 0.1249 -0.2921