LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T AZD8055
10
uM
LJP6
 2
A07
 72
hr
 765 486 3095 0.1570 -0.2015
Hs 578T AZD8055
10
uM
LJP6
 3
A07
 72
hr
 765 660 3066 0.2153 -0.0711
Hs 578T Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 765 3637 3143 1.1569 1.1482
Hs 578T Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 765 3630 3095 1.1726 1.1643
Hs 578T Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 765 3521 3066 1.1484 1.1431
Hs 578T Sorafenib
0.12
uM
LJP6
 1
B11
 72
hr
 765 3654 3143 1.1623 1.1531
Hs 578T Sorafenib
0.12
uM
LJP6
 2
B11
 72
hr
 765 3615 3095 1.1678 1.1599
Hs 578T Sorafenib
0.12
uM
LJP6
 3
B11
 72
hr
 765 3492 3066 1.1389 1.1342
Hs 578T Sorafenib
0.37
uM
LJP6
 1
B10
 72
hr
 765 3730 3143 1.1865 1.1750
Hs 578T Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 765 3724 3095 1.2030 1.1919
Hs 578T Sorafenib
0.37
uM
LJP6
 3
B10
 72
hr
 765 3850 3066 1.2557 1.2408
Hs 578T Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 765 3786 3143 1.2043 1.1909
Hs 578T Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 765 3882 3095 1.2540 1.2376
Hs 578T Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 765 3821 3066 1.2462 1.2324
Hs 578T Sorafenib
3.33
uM
LJP6
 1
B08
 72
hr
 765 3824 3143 1.2164 1.2017
Hs 578T Sorafenib
3.33
uM
LJP6
 2
B08
 72
hr
 765 3789 3095 1.2240 1.2108
Hs 578T Sorafenib
3.33
uM
LJP6
 3
B08
 72
hr
 765 3697 3066 1.2058 1.1959
Hs 578T Sorafenib
10
uM
LJP6
 1
B07
 72
hr
 765 2830 3143 0.9002 0.8995
Hs 578T Sorafenib
10
uM
LJP6
 2
B07
 72
hr
 765 3027 3095 0.9778 0.9779
Hs 578T Sorafenib
10
uM
LJP6
 3
B07
 72
hr
 765 2707 3066 0.8829 0.8794
Hs 578T CP466722
0.04
uM
LJP5
 1
I12
 72
hr
 765 3160 3140 1.0063 1.0061
Hs 578T CP466722
0.04
uM
LJP5
 2
I12
 72
hr
 765 3318 3151 1.0528 1.0510
Hs 578T CP466722
0.04
uM
LJP5
 3
I12
 72
hr
 765 3230 3152 1.0246 1.0239
Hs 578T CP466722
0.12
uM
LJP5
 1
I11
 72
hr
 765 3263 3140 1.0391 1.0380
Hs 578T CP466722
0.12
uM
LJP5
 2
I11
 72
hr
 765 3184 3151 1.0103 1.0100