LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Buparlisib
0.04
uM
LJP5
 3
H06
 72
hr
 1311 5397 5010 1.0771 1.0783
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 1
H05
 72
hr
 1311 4974 5128 0.9699 0.9692
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 2
H05
 72
hr
 1311 4866 5100 0.9541 0.9526
MDA-MB-231 Buparlisib
0.12
uM
LJP5
 3
H05
 72
hr
 1311 5042 5010 1.0062 1.0064
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 1
H04
 72
hr
 1311 4544 5128 0.8861 0.8807
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 2
H04
 72
hr
 1311 4521 5100 0.8865 0.8807
MDA-MB-231 Buparlisib
0.37
uM
LJP5
 3
H04
 72
hr
 1311 4507 5010 0.8995 0.8933
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 1
H03
 72
hr
 1311 2828 5128 0.5514 0.4778
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 2
H03
 72
hr
 1311 2722 5100 0.5337 0.4516
MDA-MB-231 Buparlisib
1.11
uM
LJP5
 3
H03
 72
hr
 1311 2739 5010 0.5466 0.4634
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 1
H02
 72
hr
 1311 1730 5128 0.3373 0.1511
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 2
H02
 72
hr
 1311 1552 5100 0.3043 0.0897
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 3
H02
 72
hr
 1311 1539 5010 0.3071 0.0862
MDA-MB-231 Buparlisib
10
uM
LJP5
 1
H01
 72
hr
 1311 727 5128 0.1418 -0.2592
MDA-MB-231 Buparlisib
10
uM
LJP5
 2
H01
 72
hr
 1311 735 5100 0.1441 -0.2560
MDA-MB-231 Buparlisib
10
uM
LJP5
 3
H01
 72
hr
 1311 743 5010 0.1483 -0.2547
MDA-MB-231 XL147
0.04
uM
LJP5
 1
G12
 72
hr
 1311 5097 5128 0.9939 0.9938
MDA-MB-231 XL147
0.04
uM
LJP5
 2
G12
 72
hr
 1311 5190 5100 1.0176 1.0179
MDA-MB-231 XL147
0.04
uM
LJP5
 3
G12
 72
hr
 1311 5254 5010 1.0485 1.0496
MDA-MB-231 XL147
0.12
uM
LJP5
 1
G11
 72
hr
 1311 4663 5128 0.9093 0.9056
MDA-MB-231 XL147
0.12
uM
LJP5
 2
G11
 72
hr
 1311 4947 5100 0.9700 0.9691
MDA-MB-231 XL147
0.12
uM
LJP5
 3
G11
 72
hr
 1311 4866 5010 0.9711 0.9699
MDA-MB-231 XL147
0.37
uM
LJP5
 1
G10
 72
hr
 1311 4652 5128 0.9071 0.9033
MDA-MB-231 XL147
0.37
uM
LJP5
 2
G10
 72
hr
 1311 4988 5100 0.9780 0.9775
MDA-MB-231 XL147
0.37
uM
LJP5
 3
G10
 72
hr
 1311 4909 5010 0.9797 0.9789