LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Canertinib | 10 | uM | LJP6 | 1 | H07 | 72 | hr | 1694 | 99 | 11220 | 0.0088 | -0.6470 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 2 | H07 | 72 | hr | 1694 | 106 | 11309 | 0.0094 | -0.6365 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 3 | H07 | 72 | hr | 1694 | 142 | 11121 | 0.0128 | -0.5988 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 1694 | 192 | 11042 | 0.0174 | -0.5530 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 1694 | 197 | 11220 | 0.0176 | -0.5457 |
| MCF 10A | AT-7519 | 10 | uM | LJP6 | 3 | K01 | 72 | hr | 1694 | 205 | 11121 | 0.0184 | -0.5407 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 1694 | 215 | 11220 | 0.0192 | -0.5309 |
| MCF 10A | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 1694 | 224 | 11220 | 0.0200 | -0.5238 |
| MCF 10A | Withaferin A | 10 | uM | LJP6 | 1 | G13 | 72 | hr | 1694 | 231 | 11220 | 0.0206 | -0.5184 |
| MCF 10A | Withaferin A | 10 | uM | LJP6 | 2 | G13 | 72 | hr | 1694 | 244 | 11309 | 0.0216 | -0.5072 |
| MCF 10A | Withaferin A | 10 | uM | LJP6 | 3 | G13 | 72 | hr | 1694 | 248 | 11121 | 0.0223 | -0.5073 |
| MCF 10A | Alvocidib | 0.37 | uM | LJP6 | 1 | A16 | 72 | hr | 1694 | 255 | 11220 | 0.0227 | -0.5006 |
| MCF 10A | CGP60474 | 0.12 | uM | LJP6 | 1 | G05 | 72 | hr | 1694 | 255 | 11220 | 0.0227 | -0.5006 |
| MCF 10A | Celastrol | 3.33 | uM | LJP6 | 1 | G08 | 72 | hr | 1694 | 266 | 11220 | 0.0237 | -0.4928 |
| MCF 10A | AT-7519 | 10 | uM | LJP6 | 2 | K01 | 72 | hr | 1694 | 268 | 11309 | 0.0237 | -0.4900 |
| MCF 10A | Withaferin A | 10 | uM | LJP5 | 2 | G13 | 72 | hr | 1694 | 266 | 11099 | 0.0240 | -0.4948 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 3 | G02 | 72 | hr | 1694 | 271 | 11121 | 0.0244 | -0.4909 |
| MCF 10A | CGP60474 | 1.11 | uM | LJP6 | 1 | G03 | 72 | hr | 1694 | 283 | 11220 | 0.0252 | -0.4811 |
| MCF 10A | SNS-032 | 3.33 | uM | LJP6 | 2 | H14 | 72 | hr | 1694 | 287 | 11309 | 0.0254 | -0.4771 |
| MCF 10A | CGP60474 | 0.37 | uM | LJP6 | 1 | G04 | 72 | hr | 1694 | 286 | 11220 | 0.0255 | -0.4791 |
| MCF 10A | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 1694 | 287 | 11220 | 0.0256 | -0.4785 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 1694 | 286 | 11121 | 0.0257 | -0.4807 |
| MCF 10A | SNS-032 | 1.11 | uM | LJP6 | 2 | H15 | 72 | hr | 1694 | 296 | 11309 | 0.0262 | -0.4711 |
| MCF 10A | SNS-032 | 1.11 | uM | LJP6 | 3 | H15 | 72 | hr | 1694 | 294 | 11121 | 0.0264 | -0.4754 |
| MCF 10A | Alvocidib | 10 | uM | LJP6 | 3 | A13 | 72 | hr | 1694 | 298 | 11121 | 0.0268 | -0.4728 |