LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 2543 | 239 | 5557 | 0.0430 | -0.8772 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 2543 | 298 | 5258 | 0.0567 | -0.8708 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 2543 | 348 | 5438 | 0.0640 | -0.8371 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 2543 | 423 | 5734 | 0.0738 | -0.7834 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 2543 | 479 | 5761 | 0.0831 | -0.7572 |
| SK-BR-3 | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 2543 | 602 | 5258 | 0.1145 | -0.7472 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 1 | N01 | 72 | hr | 2543 | 635 | 5258 | 0.1208 | -0.7340 |
| SK-BR-3 | LDN-193189 | 10 | uM | LJP5 | 2 | G01 | 72 | hr | 2543 | 535 | 5761 | 0.0929 | -0.7333 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP6 | 1 | G01 | 72 | hr | 2543 | 670 | 5258 | 0.1274 | -0.7200 |
| BT-20 | CGP60474 | 10 | uM | LJP6 | 1 | G01 | 72 | hr | 1334 | 182 | 3955 | 0.0460 | -0.7195 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP5 | 2 | O01 | 72 | hr | 2543 | 578 | 5761 | 0.1003 | -0.7152 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 2543 | 582 | 5760 | 0.1010 | -0.7136 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 1 | J01 | 72 | hr | 2543 | 694 | 5258 | 0.1320 | -0.7104 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 2 | J01 | 72 | hr | 2543 | 657 | 5438 | 0.1208 | -0.7091 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 1 | A16 | 72 | hr | 2543 | 714 | 5258 | 0.1358 | -0.7025 |
| SK-BR-3 | GSK1059615 | 10 | uM | LJP5 | 2 | E01 | 72 | hr | 2543 | 650 | 5761 | 0.1128 | -0.6854 |
| BT-20 | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 1334 | 219 | 3955 | 0.0554 | -0.6843 |
| BT-20 | A443654 | 10 | uM | LJP6 | 1 | I19 | 72 | hr | 1334 | 219 | 3955 | 0.0554 | -0.6843 |
| SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 2543 | 773 | 5258 | 0.1470 | -0.6791 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP6 | 3 | G01 | 72 | hr | 2543 | 707 | 5557 | 0.1272 | -0.6787 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 2 | N01 | 72 | hr | 2543 | 734 | 5438 | 0.1350 | -0.6781 |
| BT-20 | A443654 | 10 | uM | LJP6 | 2 | I19 | 72 | hr | 1334 | 233 | 3899 | 0.0598 | -0.6765 |
| BT-20 | GSK1059615 | 10 | uM | LJP6 | 1 | C01 | 72 | hr | 1334 | 228 | 3955 | 0.0576 | -0.6761 |
| SK-BR-3 | AT-7519 | 10 | uM | LJP6 | 3 | K01 | 72 | hr | 2543 | 722 | 5557 | 0.1299 | -0.6727 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 2543 | 802 | 5258 | 0.1525 | -0.6676 |