LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 2 | J03 | 72 | hr | 1389 | 1229 | 5447 | 0.2256 | -0.0602 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 3 | J03 | 72 | hr | 1389 | 1287 | 5740 | 0.2242 | -0.0366 |
| MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 1 | J02 | 72 | hr | 1389 | 659 | 5147 | 0.1280 | -0.3261 |
| MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 2 | J02 | 72 | hr | 1389 | 608 | 5447 | 0.1116 | -0.3423 |
| MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 3 | J02 | 72 | hr | 1389 | 799 | 5740 | 0.1392 | -0.2367 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 1 | J01 | 72 | hr | 1389 | 335 | 5147 | 0.0651 | -0.5289 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 2 | J01 | 72 | hr | 1389 | 257 | 5447 | 0.0472 | -0.5751 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 3 | J01 | 72 | hr | 1389 | 299 | 5740 | 0.0521 | -0.5278 |
| MCF7 | Pelitinib | 0.04 | uM | LJP5 | 1 | I18 | 72 | hr | 1389 | 6034 | 5772 | 1.0453 | 1.0436 |
| MCF7 | Pelitinib | 0.04 | uM | LJP5 | 3 | I18 | 72 | hr | 1389 | 5799 | 6038 | 0.9603 | 0.9622 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 1 | I17 | 72 | hr | 1389 | 4596 | 5772 | 0.7962 | 0.7901 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 3 | I17 | 72 | hr | 1389 | 6626 | 6038 | 1.0973 | 1.0895 |
| MCF7 | Pelitinib | 0.37 | uM | LJP5 | 1 | I16 | 72 | hr | 1389 | 4998 | 5772 | 0.8658 | 0.8646 |
| MCF7 | Pelitinib | 0.37 | uM | LJP5 | 3 | I16 | 72 | hr | 1389 | 5547 | 6038 | 0.9186 | 0.9215 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 1 | I15 | 72 | hr | 1389 | 4597 | 5772 | 0.7964 | 0.7902 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 3 | I15 | 72 | hr | 1389 | 5364 | 6038 | 0.8883 | 0.8913 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 1 | I14 | 72 | hr | 1389 | 2839 | 5772 | 0.4918 | 0.4160 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 3 | I14 | 72 | hr | 1389 | 3506 | 6038 | 0.5806 | 0.5476 |
| MCF7 | Pelitinib | 10 | uM | LJP5 | 1 | I13 | 72 | hr | 1389 | 771 | 5772 | 0.1336 | -0.2491 |
| MCF7 | Pelitinib | 10 | uM | LJP5 | 3 | I13 | 72 | hr | 1389 | 794 | 6038 | 0.1315 | -0.2319 |
| MCF7 | Luminespib | 0.04 | uM | LJP5 | 1 | H18 | 72 | hr | 1389 | 1341 | 5772 | 0.2323 | -0.0170 |
| MCF7 | Luminespib | 0.04 | uM | LJP5 | 3 | H18 | 72 | hr | 1389 | 1600 | 6038 | 0.2650 | 0.0690 |
| MCF7 | Luminespib | 0.12 | uM | LJP5 | 1 | H17 | 72 | hr | 1389 | 1403 | 5772 | 0.2431 | 0.0049 |
| MCF7 | Luminespib | 0.12 | uM | LJP5 | 3 | H17 | 72 | hr | 1389 | 1388 | 6038 | 0.2299 | -0.0004 |
| MCF7 | Luminespib | 0.37 | uM | LJP5 | 1 | H16 | 72 | hr | 1389 | 1300 | 5772 | 0.2252 | -0.0317 |