LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nintedanib | 10 | uM | LJP6 | 1 | H01 | 72 | hr | 1389 | 1549 | 5147 | 0.3010 | 0.0594 |
| MCF7 | Nintedanib | 10 | uM | LJP6 | 2 | H01 | 72 | hr | 1389 | 2645 | 5447 | 0.4855 | 0.3863 |
| MCF7 | Nintedanib | 10 | uM | LJP6 | 3 | H01 | 72 | hr | 1389 | 2208 | 5740 | 0.3846 | 0.2541 |
| MCF7 | Foretinib | 0.04 | uM | LJP5 | 1 | H12 | 72 | hr | 1389 | 5751 | 5772 | 0.9963 | 0.9964 |
| MCF7 | Foretinib | 0.04 | uM | LJP5 | 3 | H12 | 72 | hr | 1389 | 6334 | 6038 | 1.0489 | 1.0456 |
| MCF7 | Foretinib | 0.12 | uM | LJP5 | 1 | H11 | 72 | hr | 1389 | 3177 | 5772 | 0.5504 | 0.4957 |
| MCF7 | Foretinib | 0.12 | uM | LJP5 | 3 | H11 | 72 | hr | 1389 | 4419 | 6038 | 0.7318 | 0.7261 |
| MCF7 | Foretinib | 0.37 | uM | LJP5 | 1 | H10 | 72 | hr | 1389 | 1757 | 5772 | 0.3044 | 0.1211 |
| MCF7 | Foretinib | 0.37 | uM | LJP5 | 3 | H10 | 72 | hr | 1389 | 2006 | 6038 | 0.3322 | 0.1893 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 1 | H09 | 72 | hr | 1389 | 1333 | 5772 | 0.2309 | -0.0198 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 3 | H09 | 72 | hr | 1389 | 1478 | 6038 | 0.2448 | 0.0297 |
| MCF7 | Foretinib | 3.33 | uM | LJP5 | 1 | H08 | 72 | hr | 1389 | 1269 | 5772 | 0.2198 | -0.0430 |
| MCF7 | Foretinib | 3.33 | uM | LJP5 | 3 | H08 | 72 | hr | 1389 | 1482 | 6038 | 0.2454 | 0.0310 |
| MCF7 | Foretinib | 10 | uM | LJP5 | 1 | H07 | 72 | hr | 1389 | 710 | 5772 | 0.1230 | -0.2786 |
| MCF7 | Foretinib | 10 | uM | LJP5 | 3 | H07 | 72 | hr | 1389 | 854 | 6038 | 0.1414 | -0.2050 |
| MCF7 | AZD 5438 | 0.04 | uM | LJP6 | 1 | J06 | 72 | hr | 1389 | 4691 | 5147 | 0.9114 | 0.9042 |
| MCF7 | AZD 5438 | 0.04 | uM | LJP6 | 2 | J06 | 72 | hr | 1389 | 4597 | 5447 | 0.8438 | 0.8349 |
| MCF7 | AZD 5438 | 0.04 | uM | LJP6 | 3 | J06 | 72 | hr | 1389 | 5241 | 5740 | 0.9130 | 0.9130 |
| MCF7 | AZD 5438 | 0.12 | uM | LJP6 | 1 | J05 | 72 | hr | 1389 | 3105 | 5147 | 0.6033 | 0.5306 |
| MCF7 | AZD 5438 | 0.12 | uM | LJP6 | 2 | J05 | 72 | hr | 1389 | 2778 | 5447 | 0.5099 | 0.4213 |
| MCF7 | AZD 5438 | 0.12 | uM | LJP6 | 3 | J05 | 72 | hr | 1389 | 3171 | 5740 | 0.5524 | 0.4966 |
| MCF7 | AZD 5438 | 0.37 | uM | LJP6 | 1 | J04 | 72 | hr | 1389 | 1505 | 5147 | 0.2924 | 0.0433 |
| MCF7 | AZD 5438 | 0.37 | uM | LJP6 | 2 | J04 | 72 | hr | 1389 | 1492 | 5447 | 0.2739 | 0.0369 |
| MCF7 | AZD 5438 | 0.37 | uM | LJP6 | 3 | J04 | 72 | hr | 1389 | 1724 | 5740 | 0.3003 | 0.1113 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 1 | J03 | 72 | hr | 1389 | 1154 | 5147 | 0.2242 | -0.0935 |