LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Withaferin A
0.12
uM
LJP5
 1
G17
 72
hr
 1389 5367 5772 0.9298 0.9304
MCF7 Withaferin A
0.12
uM
LJP5
 3
G17
 72
hr
 1389 5427 6038 0.8987 0.9018
MCF7 Withaferin A
0.37
uM
LJP6
 1
G16
 72
hr
 1389 2412 5147 0.4686 0.3391
MCF7 Withaferin A
0.37
uM
LJP6
 2
G16
 72
hr
 1389 2677 5447 0.4914 0.3948
MCF7 Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 1389 2682 5740 0.4672 0.3791
MCF7 Withaferin A
0.37
uM
LJP5
 1
G16
 72
hr
 1389 2876 5772 0.4982 0.4249
MCF7 Withaferin A
0.37
uM
LJP5
 3
G16
 72
hr
 1389 2903 6038 0.4808 0.4158
MCF7 Withaferin A
1.11
uM
LJP6
 1
G15
 72
hr
 1389 1517 5147 0.2947 0.0477
MCF7 Withaferin A
1.11
uM
LJP6
 2
G15
 72
hr
 1389 1716 5447 0.3150 0.1132
MCF7 Withaferin A
1.11
uM
LJP6
 3
G15
 72
hr
 1389 1802 5740 0.3139 0.1356
MCF7 Withaferin A
1.11
uM
LJP5
 1
G15
 72
hr
 1389 1684 5772 0.2917 0.0982
MCF7 Withaferin A
1.11
uM
LJP5
 3
G15
 72
hr
 1389 1833 6038 0.3036 0.1398
MCF7 Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 1389 993 5147 0.1929 -0.1628
MCF7 Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 1389 1118 5447 0.2052 -0.1043
MCF7 Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 1389 1037 5740 0.1807 -0.1331
MCF7 Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 1389 1180 5772 0.2044 -0.0763
MCF7 Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 1389 883 6038 0.1462 -0.1924
MCF7 Withaferin A
10
uM
LJP6
 1
G13
 72
hr
 1389 1141 5147 0.2217 -0.0989
MCF7 Withaferin A
10
uM
LJP6
 2
G13
 72
hr
 1389 989 5447 0.1815 -0.1583
MCF7 Withaferin A
10
uM
LJP6
 3
G13
 72
hr
 1389 1413 5740 0.2462 0.0084
MCF7 Withaferin A
10
uM
LJP5
 1
G13
 72
hr
 1389 1162 5772 0.2013 -0.0832
MCF7 Withaferin A
10
uM
LJP5
 3
G13
 72
hr
 1389 1222 6038 0.2024 -0.0587
MCF7
LJP6
 1
A03
 72
hr
 1389 4339 5147 0.8430 0.8272
MCF7
LJP6
 1
A04
 72
hr
 1389 4275 5147 0.8306 0.8129
MCF7
LJP6
 1
A05
 72
hr
 1389 3745 5147 0.7276 0.6902