LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A GSK1059615
1.11
uM
LJP6
 2
C03
 72
hr
 1694 3341 11309 0.2954 0.2814
MCF 10A GSK1059615
1.11
uM
LJP6
 3
C03
 72
hr
 1694 2512 11121 0.2259 0.1561
MCF 10A GSK1059615
1.11
uM
LJP5
 1
E03
 72
hr
 1694 2724 11042 0.2467 0.1920
MCF 10A GSK1059615
1.11
uM
LJP5
 2
E03
 72
hr
 1694 2696 11099 0.2429 0.1869
MCF 10A GSK1059615
1.11
uM
LJP5
 3
E03
 72
hr
 1694 2370 11168 0.2122 0.1313
MCF 10A GSK1059615
3.33
uM
LJP6
 1
C02
 72
hr
 1694 2298 11220 0.2048 0.1182
MCF 10A GSK1059615
3.33
uM
LJP6
 2
C02
 72
hr
 1694 2152 11309 0.1903 0.0912
MCF 10A GSK1059615
3.33
uM
LJP6
 3
C02
 72
hr
 1694 1646 11121 0.1480 -0.0106
MCF 10A GSK1059615
3.33
uM
LJP5
 1
E02
 72
hr
 1694 1089 11042 0.0986 -0.1508
MCF 10A GSK1059615
3.33
uM
LJP5
 2
E02
 72
hr
 1694 1525 11099 0.1374 -0.0381
MCF 10A GSK1059615
3.33
uM
LJP5
 3
E02
 72
hr
 1694 1416 11168 0.1268 -0.0638
MCF 10A GSK1059615
10
uM
LJP6
 1
C01
 72
hr
 1694 1703 11220 0.1518 0.0019
MCF 10A GSK1059615
10
uM
LJP6
 2
C01
 72
hr
 1694 1602 11309 0.1417 -0.0202
MCF 10A GSK1059615
10
uM
LJP6
 3
C01
 72
hr
 1694 1197 11121 0.1076 -0.1201
MCF 10A GSK1059615
10
uM
LJP5
 1
E01
 72
hr
 1694 1439 11042 0.1303 -0.0586
MCF 10A GSK1059615
10
uM
LJP5
 2
E01
 72
hr
 1694 1545 11099 0.1392 -0.0334
MCF 10A GSK1059615
10
uM
LJP5
 3
E01
 72
hr
 1694 1424 11168 0.1275 -0.0619
MCF 10A Brivanib
0.04
uM
LJP5
 1
P18
 72
hr
 1694 11236 11042 1.0175 1.0129
MCF 10A Brivanib
0.04
uM
LJP5
 2
P18
 72
hr
 1694 10941 11099 0.9857 0.9894
MCF 10A Brivanib
0.04
uM
LJP5
 3
P18
 72
hr
 1694 11224 11168 1.0050 1.0037
MCF 10A Brivanib
0.12
uM
LJP5
 1
P17
 72
hr
 1694 10862 11042 0.9837 0.9879
MCF 10A Brivanib
0.12
uM
LJP5
 2
P17
 72
hr
 1694 10855 11099 0.9780 0.9836
MCF 10A Brivanib
0.12
uM
LJP5
 3
P17
 72
hr
 1694 10605 11168 0.9496 0.9623
MCF 10A Brivanib
0.37
uM
LJP5
 1
P16
 72
hr
 1694 10659 11042 0.9653 0.9740
MCF 10A Brivanib
0.37
uM
LJP5
 2
P16
 72
hr
 1694 10814 11099 0.9743 0.9809