LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 1694 10900 11042 0.9871 0.9904
MCF 10A Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 1694 10242 11099 0.9227 0.9416
MCF 10A Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 1694 10880 11168 0.9742 0.9809
MCF 10A Fedratinib
0.37
uM
LJP5
 1
L04
 72
hr
 1694 10418 11042 0.9435 0.9574
MCF 10A Fedratinib
0.37
uM
LJP5
 2
L04
 72
hr
 1694 10070 11099 0.9073 0.9295
MCF 10A Fedratinib
0.37
uM
LJP5
 3
L04
 72
hr
 1694 10576 11168 0.9470 0.9603
MCF 10A Fedratinib
1.11
uM
LJP5
 1
L03
 72
hr
 1694 10131 11042 0.9175 0.9373
MCF 10A Fedratinib
1.11
uM
LJP5
 2
L03
 72
hr
 1694 9587 11099 0.8637 0.8948
MCF 10A Fedratinib
1.11
uM
LJP5
 3
L03
 72
hr
 1694 10019 11168 0.8971 0.9217
MCF 10A Fedratinib
3.33
uM
LJP5
 1
L02
 72
hr
 1694 6996 11042 0.6336 0.6894
MCF 10A Fedratinib
3.33
uM
LJP5
 2
L02
 72
hr
 1694 6663 11099 0.6003 0.6569
MCF 10A Fedratinib
3.33
uM
LJP5
 3
L02
 72
hr
 1694 7413 11168 0.6638 0.7203
MCF 10A Fedratinib
10
uM
LJP5
 1
L01
 72
hr
 1694 1891 11042 0.1713 0.0415
MCF 10A Fedratinib
10
uM
LJP5
 2
L01
 72
hr
 1694 2363 11099 0.2129 0.1305
MCF 10A Fedratinib
10
uM
LJP5
 3
L01
 72
hr
 1694 2195 11168 0.1965 0.0999
MCF 10A Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 1694 2800 11042 0.2536 0.2041
MCF 10A Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 1694 2568 11099 0.2314 0.1658
MCF 10A Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 1694 2900 11168 0.2597 0.2184
MCF 10A Trametinib
0.12
uM
LJP5
 1
P23
 72
hr
 1694 3024 11042 0.2739 0.2389
MCF 10A Trametinib
0.12
uM
LJP5
 2
P23
 72
hr
 1694 3135 11099 0.2825 0.2547
MCF 10A Trametinib
0.12
uM
LJP5
 3
P23
 72
hr
 1694 2792 11168 0.2500 0.2015
MCF 10A Trametinib
0.37
uM
LJP5
 1
P22
 72
hr
 1694 3106 11042 0.2813 0.2512
MCF 10A Trametinib
0.37
uM
LJP5
 2
P22
 72
hr
 1694 3240 11099 0.2919 0.2701
MCF 10A Trametinib
0.37
uM
LJP5
 3
P22
 72
hr
 1694 2788 11168 0.2496 0.2009
MCF 10A Trametinib
1.11
uM
LJP5
 1
P21
 72
hr
 1694 3333 11042 0.3018 0.2843