LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Trametinib
1.11
uM
LJP5
 2
P21
 72
hr
 1694 3165 11099 0.2852 0.2592
MCF 10A Trametinib
1.11
uM
LJP5
 3
P21
 72
hr
 1694 3268 11168 0.2926 0.2731
MCF 10A Trametinib
3.33
uM
LJP5
 1
P20
 72
hr
 1694 3246 11042 0.2940 0.2718
MCF 10A Trametinib
3.33
uM
LJP5
 2
P20
 72
hr
 1694 3047 11099 0.2745 0.2416
MCF 10A Trametinib
3.33
uM
LJP5
 3
P20
 72
hr
 1694 3106 11168 0.2781 0.2495
MCF 10A Trametinib
10
uM
LJP5
 1
P19
 72
hr
 1694 3266 11042 0.2958 0.2747
MCF 10A Trametinib
10
uM
LJP5
 2
P19
 72
hr
 1694 3268 11099 0.2944 0.2741
MCF 10A Trametinib
10
uM
LJP5
 3
P19
 72
hr
 1694 3568 11168 0.3195 0.3149
MCF 10A Omipalisib
0.04
uM
LJP6
 1
N06
 72
hr
 1694 2196 11220 0.1957 0.0998
MCF 10A Omipalisib
0.04
uM
LJP6
 2
N06
 72
hr
 1694 2329 11309 0.2059 0.1232
MCF 10A Omipalisib
0.04
uM
LJP6
 3
N06
 72
hr
 1694 2174 11121 0.1955 0.0962
MCF 10A Omipalisib
0.12
uM
LJP6
 1
N05
 72
hr
 1694 1738 11220 0.1549 0.0094
MCF 10A Omipalisib
0.12
uM
LJP6
 2
N05
 72
hr
 1694 1991 11309 0.1761 0.0607
MCF 10A Omipalisib
0.12
uM
LJP6
 3
N05
 72
hr
 1694 1782 11121 0.1602 0.0188
MCF 10A Omipalisib
0.37
uM
LJP6
 1
N04
 72
hr
 1694 1633 11220 0.1455 -0.0134
MCF 10A Omipalisib
0.37
uM
LJP6
 2
N04
 72
hr
 1694 1751 11309 0.1548 0.0121
MCF 10A Omipalisib
0.37
uM
LJP6
 3
N04
 72
hr
 1694 1807 11121 0.1625 0.0240
MCF 10A Omipalisib
1.11
uM
LJP6
 1
N03
 72
hr
 1694 1476 11220 0.1315 -0.0493
MCF 10A Omipalisib
1.11
uM
LJP6
 2
N03
 72
hr
 1694 1859 11309 0.1644 0.0345
MCF 10A Omipalisib
1.11
uM
LJP6
 3
N03
 72
hr
 1694 1573 11121 0.1414 -0.0270
MCF 10A Omipalisib
3.33
uM
LJP6
 1
N02
 72
hr
 1694 1259 11220 0.1122 -0.1032
MCF 10A Omipalisib
3.33
uM
LJP6
 2
N02
 72
hr
 1694 1546 11309 0.1367 -0.0329
MCF 10A Omipalisib
3.33
uM
LJP6
 3
N02
 72
hr
 1694 1692 11121 0.1521 -0.0005
MCF 10A Omipalisib
10
uM
LJP6
 1
N01
 72
hr
 1694 860 11220 0.0766 -0.2201
MCF 10A Omipalisib
10
uM
LJP6
 2
N01
 72
hr
 1694 894 11309 0.0791 -0.2082