LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A SU11274
3.33
uM
LJP5
 1
J08
 72
hr
 1694 7399 11042 0.6701 0.7248
MCF 10A SU11274
3.33
uM
LJP5
 2
J08
 72
hr
 1694 7296 11099 0.6573 0.7133
MCF 10A SU11274
3.33
uM
LJP5
 3
J08
 72
hr
 1694 7764 11168 0.6952 0.7498
MCF 10A SU11274
10
uM
LJP5
 1
J07
 72
hr
 1694 5074 11042 0.4595 0.5002
MCF 10A SU11274
10
uM
LJP5
 2
J07
 72
hr
 1694 5240 11099 0.4721 0.5164
MCF 10A SU11274
10
uM
LJP5
 3
J07
 72
hr
 1694 5260 11168 0.4710 0.5165
MCF 10A Canertinib
0.04
uM
LJP6
 1
H12
 72
hr
 1694 9084 11220 0.8096 0.8509
MCF 10A Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 1694 8975 11309 0.7936 0.8381
MCF 10A Canertinib
0.04
uM
LJP6
 3
H12
 72
hr
 1694 9266 11121 0.8332 0.8700
MCF 10A Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 1694 6375 11220 0.5681 0.6256
MCF 10A Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 1694 6064 11309 0.5362 0.5929
MCF 10A Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 1694 7040 11121 0.6330 0.6900
MCF 10A Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 1694 4107 11220 0.3660 0.3835
MCF 10A Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 1694 4000 11309 0.3537 0.3684
MCF 10A Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 1694 4659 11121 0.4189 0.4516
MCF 10A Canertinib
1.11
uM
LJP6
 1
H09
 72
hr
 1694 2862 11220 0.2551 0.2119
MCF 10A Canertinib
1.11
uM
LJP6
 2
H09
 72
hr
 1694 2409 11309 0.2130 0.1371
MCF 10A Canertinib
1.11
uM
LJP6
 3
H09
 72
hr
 1694 2944 11121 0.2647 0.2257
MCF 10A Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 1694 2362 11220 0.2105 0.1296
MCF 10A Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 1694 2131 11309 0.1884 0.0873
MCF 10A Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 1694 2193 11121 0.1972 0.0997
MCF 10A Canertinib
10
uM
LJP6
 1
H07
 72
hr
 1694 99 11220 0.0088 -0.6470
MCF 10A Canertinib
10
uM
LJP6
 2
H07
 72
hr
 1694 106 11309 0.0094 -0.6365
MCF 10A Canertinib
10
uM
LJP6
 3
H07
 72
hr
 1694 142 11121 0.0128 -0.5988
MCF 10A NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 1694 10857 11042 0.9832 0.9875