LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A AZD 5438
1.11
uM
LJP6
 1
J03
 72
hr
 1694 1765 11220 0.1573 0.0151
MCF 10A AZD 5438
1.11
uM
LJP6
 2
J03
 72
hr
 1694 1652 11309 0.1461 -0.0092
MCF 10A AZD 5438
1.11
uM
LJP6
 3
J03
 72
hr
 1694 1615 11121 0.1452 -0.0175
MCF 10A AZD 5438
3.33
uM
LJP6
 1
J02
 72
hr
 1694 643 11220 0.0573 -0.2990
MCF 10A AZD 5438
3.33
uM
LJP6
 2
J02
 72
hr
 1694 479 11309 0.0424 -0.3695
MCF 10A AZD 5438
3.33
uM
LJP6
 3
J02
 72
hr
 1694 418 11121 0.0376 -0.4028
MCF 10A AZD 5438
10
uM
LJP6
 1
J01
 72
hr
 1694 573 11220 0.0511 -0.3280
MCF 10A AZD 5438
10
uM
LJP6
 2
J01
 72
hr
 1694 565 11309 0.0500 -0.3303
MCF 10A AZD 5438
10
uM
LJP6
 3
J01
 72
hr
 1694 585 11121 0.0526 -0.3241
MCF 10A Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 1694 8812 11042 0.7980 0.8399
MCF 10A Pelitinib
0.04
uM
LJP5
 2
I18
 72
hr
 1694 8586 11099 0.7736 0.8193
MCF 10A Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 1694 8700 11168 0.7790 0.8246
MCF 10A Pelitinib
0.12
uM
LJP5
 1
I17
 72
hr
 1694 5862 11042 0.5309 0.5825
MCF 10A Pelitinib
0.12
uM
LJP5
 2
I17
 72
hr
 1694 5652 11099 0.5092 0.5594
MCF 10A Pelitinib
0.12
uM
LJP5
 3
I17
 72
hr
 1694 5908 11168 0.5290 0.5827
MCF 10A Pelitinib
0.37
uM
LJP5
 1
I16
 72
hr
 1694 2555 11042 0.2314 0.1641
MCF 10A Pelitinib
0.37
uM
LJP5
 2
I16
 72
hr
 1694 2409 11099 0.2170 0.1386
MCF 10A Pelitinib
0.37
uM
LJP5
 3
I16
 72
hr
 1694 2683 11168 0.2402 0.1841
MCF 10A Pelitinib
1.11
uM
LJP5
 1
I15
 72
hr
 1694 2755 11042 0.2495 0.1970
MCF 10A Pelitinib
1.11
uM
LJP5
 2
I15
 72
hr
 1694 2492 11099 0.2245 0.1529
MCF 10A Pelitinib
1.11
uM
LJP5
 3
I15
 72
hr
 1694 2599 11168 0.2327 0.1703
MCF 10A Pelitinib
3.33
uM
LJP5
 1
I14
 72
hr
 1694 2413 11042 0.2185 0.1397
MCF 10A Pelitinib
3.33
uM
LJP5
 2
I14
 72
hr
 1694 2356 11099 0.2123 0.1293
MCF 10A Pelitinib
3.33
uM
LJP5
 3
I14
 72
hr
 1694 2591 11168 0.2320 0.1690
MCF 10A Pelitinib
10
uM
LJP5
 1
I13
 72
hr
 1694 1636 11042 0.1482 -0.0129