LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Foretinib
0.04
uM
LJP5
 3
H12
 72
hr
 1694 11753 11168 1.0523 1.0379
MCF 10A Foretinib
0.12
uM
LJP5
 1
H11
 72
hr
 1694 11495 11042 1.0410 1.0299
MCF 10A Foretinib
0.12
uM
LJP5
 2
H11
 72
hr
 1694 11165 11099 1.0059 1.0043
MCF 10A Foretinib
0.12
uM
LJP5
 3
H11
 72
hr
 1694 11488 11168 1.0286 1.0209
MCF 10A Foretinib
0.37
uM
LJP5
 1
H10
 72
hr
 1694 10246 11042 0.9279 0.9454
MCF 10A Foretinib
0.37
uM
LJP5
 2
H10
 72
hr
 1694 10207 11099 0.9196 0.9391
MCF 10A Foretinib
0.37
uM
LJP5
 3
H10
 72
hr
 1694 10223 11168 0.9154 0.9360
MCF 10A Foretinib
1.11
uM
LJP5
 1
H09
 72
hr
 1694 4981 11042 0.4511 0.4900
MCF 10A Foretinib
1.11
uM
LJP5
 2
H09
 72
hr
 1694 5964 11099 0.5373 0.5906
MCF 10A Foretinib
1.11
uM
LJP5
 3
H09
 72
hr
 1694 5631 11168 0.5042 0.5550
MCF 10A Foretinib
3.33
uM
LJP5
 1
H08
 72
hr
 1694 2283 11042 0.2068 0.1166
MCF 10A Foretinib
3.33
uM
LJP5
 2
H08
 72
hr
 1694 2335 11099 0.2104 0.1256
MCF 10A Foretinib
3.33
uM
LJP5
 3
H08
 72
hr
 1694 2358 11168 0.2111 0.1292
MCF 10A Foretinib
10
uM
LJP5
 1
H07
 72
hr
 1694 1366 11042 0.1237 -0.0765
MCF 10A Foretinib
10
uM
LJP5
 2
H07
 72
hr
 1694 1557 11099 0.1403 -0.0307
MCF 10A Foretinib
10
uM
LJP5
 3
H07
 72
hr
 1694 1328 11168 0.1189 -0.0856
MCF 10A AZD 5438
0.04
uM
LJP6
 1
J06
 72
hr
 1694 10828 11220 0.9650 0.9740
MCF 10A AZD 5438
0.04
uM
LJP6
 2
J06
 72
hr
 1694 11033 11309 0.9756 0.9820
MCF 10A AZD 5438
0.04
uM
LJP6
 3
J06
 72
hr
 1694 10884 11121 0.9787 0.9842
MCF 10A AZD 5438
0.12
uM
LJP6
 1
J05
 72
hr
 1694 9465 11220 0.8435 0.8790
MCF 10A AZD 5438
0.12
uM
LJP6
 2
J05
 72
hr
 1694 9998 11309 0.8841 0.9120
MCF 10A AZD 5438
0.12
uM
LJP6
 3
J05
 72
hr
 1694 9598 11121 0.8630 0.8944
MCF 10A AZD 5438
0.37
uM
LJP6
 1
J04
 72
hr
 1694 6393 11220 0.5697 0.6272
MCF 10A AZD 5438
0.37
uM
LJP6
 2
J04
 72
hr
 1694 6561 11309 0.5801 0.6394
MCF 10A AZD 5438
0.37
uM
LJP6
 3
J04
 72
hr
 1694 6286 11121 0.5652 0.6209