LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Mitoxantrone
0.12
uM
LJP6
 2
C23
 72
hr
 1694 1538 11309 0.1360 -0.0347
MCF 10A Mitoxantrone
0.12
uM
LJP6
 3
C23
 72
hr
 1694 1649 11121 0.1483 -0.0099
MCF 10A Mitoxantrone
0.12
uM
LJP5
 1
C23
 72
hr
 1694 1709 11042 0.1548 0.0032
MCF 10A Mitoxantrone
0.12
uM
LJP5
 2
C23
 72
hr
 1694 1687 11099 0.1520 -0.0016
MCF 10A Mitoxantrone
0.12
uM
LJP5
 3
C23
 72
hr
 1694 1665 11168 0.1491 -0.0064
MCF 10A Mitoxantrone
0.37
uM
LJP6
 1
C22
 72
hr
 1694 1460 11220 0.1301 -0.0531
MCF 10A Mitoxantrone
0.37
uM
LJP6
 2
C22
 72
hr
 1694 1441 11309 0.1274 -0.0574
MCF 10A Mitoxantrone
0.37
uM
LJP6
 3
C22
 72
hr
 1694 1536 11121 0.1381 -0.0355
MCF 10A Mitoxantrone
0.37
uM
LJP5
 1
C22
 72
hr
 1694 1624 11042 0.1471 -0.0155
MCF 10A Mitoxantrone
0.37
uM
LJP5
 2
C22
 72
hr
 1694 1601 11099 0.1442 -0.0207
MCF 10A Mitoxantrone
0.37
uM
LJP5
 3
C22
 72
hr
 1694 1646 11168 0.1474 -0.0106
MCF 10A Mitoxantrone
1.11
uM
LJP6
 1
C21
 72
hr
 1694 1343 11220 0.1197 -0.0817
MCF 10A Mitoxantrone
1.11
uM
LJP6
 2
C21
 72
hr
 1694 1370 11309 0.1211 -0.0746
MCF 10A Mitoxantrone
1.11
uM
LJP6
 3
C21
 72
hr
 1694 1428 11121 0.1284 -0.0610
MCF 10A Mitoxantrone
1.11
uM
LJP5
 1
C21
 72
hr
 1694 1311 11042 0.1187 -0.0905
MCF 10A Mitoxantrone
1.11
uM
LJP5
 2
C21
 72
hr
 1694 1551 11099 0.1397 -0.0321
MCF 10A Mitoxantrone
1.11
uM
LJP5
 3
C21
 72
hr
 1694 1405 11168 0.1258 -0.0665
MCF 10A Mitoxantrone
3.33
uM
LJP6
 1
C20
 72
hr
 1694 641 11220 0.0571 -0.2998
MCF 10A Mitoxantrone
3.33
uM
LJP6
 2
C20
 72
hr
 1694 482 11309 0.0426 -0.3681
MCF 10A Mitoxantrone
3.33
uM
LJP6
 3
C20
 72
hr
 1694 767 11121 0.0690 -0.2532
MCF 10A Mitoxantrone
3.33
uM
LJP5
 1
C20
 72
hr
 1694 795 11042 0.0720 -0.2441
MCF 10A Mitoxantrone
3.33
uM
LJP5
 2
C20
 72
hr
 1694 845 11099 0.0761 -0.2263
MCF 10A Mitoxantrone
3.33
uM
LJP5
 3
C20
 72
hr
 1694 686 11168 0.0614 -0.2827
MCF 10A Mitoxantrone
10
uM
LJP6
 1
C19
 72
hr
 1694 707 11220 0.0630 -0.2742
MCF 10A Mitoxantrone
10
uM
LJP6
 2
C19
 72
hr
 1694 776 11309 0.0686 -0.2481