LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 1694 6697 11121 0.6022 0.6592
MCF 10A WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 1694 3840 11220 0.3422 0.3499
MCF 10A WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 1694 3989 11309 0.3527 0.3671
MCF 10A WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 1694 3748 11121 0.3370 0.3398
MCF 10A WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 1694 3276 11220 0.2920 0.2735
MCF 10A WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 1694 3530 11309 0.3121 0.3074
MCF 10A WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 1694 3004 11121 0.2701 0.2349
MCF 10A WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 1694 2796 11220 0.2492 0.2016
MCF 10A WYE-125132
1.11
uM
LJP6
 2
L09
 72
hr
 1694 2822 11309 0.2495 0.2048
MCF 10A WYE-125132
1.11
uM
LJP6
 3
L09
 72
hr
 1694 2613 11121 0.2350 0.1731
MCF 10A WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 1694 2582 11220 0.2301 0.1670
MCF 10A WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 1694 2942 11309 0.2601 0.2232
MCF 10A WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 1694 2816 11121 0.2532 0.2058
MCF 10A WYE-125132
10
uM
LJP6
 1
L07
 72
hr
 1694 2588 11220 0.2306 0.1680
MCF 10A WYE-125132
10
uM
LJP6
 2
L07
 72
hr
 1694 2573 11309 0.2275 0.1648
MCF 10A WYE-125132
10
uM
LJP6
 3
L07
 72
hr
 1694 2635 11121 0.2369 0.1767
MCF 10A Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 1694 2379 11042 0.2154 0.1337
MCF 10A Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 1694 3039 11099 0.2738 0.2404
MCF 10A Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 1694 2654 11168 0.2376 0.1794
MCF 10A Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 1694 1866 11042 0.1690 0.0363
MCF 10A Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 1694 1921 11099 0.1731 0.0474
MCF 10A Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 1694 1974 11168 0.1768 0.0578
MCF 10A Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 1694 1878 11042 0.1701 0.0388
MCF 10A Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 1694 2018 11099 0.1818 0.0666
MCF 10A Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 1694 2001 11168 0.1792 0.0631