LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Barasertib
1.11
uM
LJP5
 1
D09
 72
hr
 1694 1879 11042 0.1702 0.0390
MCF 10A Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 1694 2025 11099 0.1824 0.0680
MCF 10A Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 1694 2077 11168 0.1860 0.0777
MCF 10A Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 1694 1986 11042 0.1799 0.0605
MCF 10A Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 1694 2173 11099 0.1958 0.0961
MCF 10A Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 1694 2113 11168 0.1892 0.0846
MCF 10A Barasertib
10
uM
LJP5
 1
D07
 72
hr
 1694 2080 11042 0.1884 0.0788
MCF 10A Barasertib
10
uM
LJP5
 2
D07
 72
hr
 1694 1971 11099 0.1776 0.0574
MCF 10A Barasertib
10
uM
LJP5
 3
D07
 72
hr
 1694 2098 11168 0.1879 0.0817
MCF 10A Vemurafenib
0.04
uM
LJP5
 1
C18
 72
hr
 1694 10731 11042 0.9718 0.9790
MCF 10A Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 1694 11286 11099 1.0168 1.0123
MCF 10A Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 1694 10873 11168 0.9736 0.9804
MCF 10A Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 1694 10605 11042 0.9604 0.9703
MCF 10A Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 1694 11177 11099 1.0070 1.0051
MCF 10A Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 1694 10790 11168 0.9661 0.9748
MCF 10A Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 1694 10839 11042 0.9816 0.9863
MCF 10A Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 1694 11162 11099 1.0056 1.0041
MCF 10A Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 1694 10917 11168 0.9775 0.9833
MCF 10A Vemurafenib
1.11
uM
LJP5
 1
C15
 72
hr
 1694 10636 11042 0.9632 0.9725
MCF 10A Vemurafenib
1.11
uM
LJP5
 2
C15
 72
hr
 1694 11085 11099 0.9987 0.9990
MCF 10A Vemurafenib
1.11
uM
LJP5
 3
C15
 72
hr
 1694 10891 11168 0.9752 0.9816
MCF 10A Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 1694 9040 11042 0.8187 0.8574
MCF 10A Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 1694 9507 11099 0.8565 0.8890
MCF 10A Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 1694 8778 11168 0.7860 0.8306
MCF 10A Vemurafenib
10
uM
LJP5
 1
C13
 72
hr
 1694 4983 11042 0.4513 0.4902