LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A NU7441
3.33
uM
LJP5
 2
C08
 72
hr
 1694 10356 11099 0.9330 0.9495
MCF 10A NU7441
3.33
uM
LJP5
 3
C08
 72
hr
 1694 10071 11168 0.9017 0.9254
MCF 10A NU7441
10
uM
LJP5
 1
C07
 72
hr
 1694 6820 11042 0.6176 0.6736
MCF 10A NU7441
10
uM
LJP5
 2
C07
 72
hr
 1694 7628 11099 0.6872 0.7417
MCF 10A NU7441
10
uM
LJP5
 3
C07
 72
hr
 1694 7173 11168 0.6423 0.6996
MCF 10A OSI-027
0.04
uM
LJP6
 1
E12
 72
hr
 1694 10810 11220 0.9634 0.9728
MCF 10A OSI-027
0.04
uM
LJP6
 2
E12
 72
hr
 1694 10418 11309 0.9212 0.9409
MCF 10A OSI-027
0.04
uM
LJP6
 3
E12
 72
hr
 1694 10486 11121 0.9429 0.9571
MCF 10A OSI-027
0.12
uM
LJP6
 1
E11
 72
hr
 1694 8501 11220 0.7576 0.8065
MCF 10A OSI-027
0.12
uM
LJP6
 2
E11
 72
hr
 1694 8175 11309 0.7229 0.7765
MCF 10A OSI-027
0.12
uM
LJP6
 3
E11
 72
hr
 1694 8387 11121 0.7542 0.8026
MCF 10A OSI-027
0.37
uM
LJP6
 1
E10
 72
hr
 1694 6042 11220 0.5385 0.5939
MCF 10A OSI-027
0.37
uM
LJP6
 2
E10
 72
hr
 1694 5929 11309 0.5243 0.5799
MCF 10A OSI-027
0.37
uM
LJP6
 3
E10
 72
hr
 1694 6332 11121 0.5694 0.6253
MCF 10A OSI-027
1.11
uM
LJP6
 1
E09
 72
hr
 1694 4035 11220 0.3596 0.3746
MCF 10A OSI-027
1.11
uM
LJP6
 2
E09
 72
hr
 1694 3845 11309 0.3400 0.3488
MCF 10A OSI-027
1.11
uM
LJP6
 3
E09
 72
hr
 1694 4477 11121 0.4026 0.4304
MCF 10A OSI-027
3.33
uM
LJP6
 1
E08
 72
hr
 1694 3520 11220 0.3137 0.3075
MCF 10A OSI-027
3.33
uM
LJP6
 2
E08
 72
hr
 1694 3537 11309 0.3128 0.3083
MCF 10A OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 1694 3494 11121 0.3142 0.3056
MCF 10A OSI-027
10
uM
LJP6
 1
E07
 72
hr
 1694 2893 11220 0.2578 0.2167
MCF 10A OSI-027
10
uM
LJP6
 2
E07
 72
hr
 1694 2283 11309 0.2019 0.1151
MCF 10A OSI-027
10
uM
LJP6
 3
E07
 72
hr
 1694 2571 11121 0.2312 0.1661
MCF 10A WYE-125132
0.04
uM
LJP6
 1
L12
 72
hr
 1694 7140 11220 0.6363 0.6945
MCF 10A WYE-125132
0.04
uM
LJP6
 2
L12
 72
hr
 1694 6878 11309 0.6082 0.6679