LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 1
O05
 72
hr
 1311 1728 5128 0.3370 0.1504
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 2
O05
 72
hr
 1311 1958 5100 0.3839 0.2269
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 3
O05
 72
hr
 1311 1545 5010 0.3083 0.0883
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 1
O04
 72
hr
 1311 1162 4870 0.2386 -0.0620
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 2
O04
 72
hr
 1311 1347 4961 0.2715 0.0139
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 3
O04
 72
hr
 1311 1232 4973 0.2477 -0.0321
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 1
O04
 72
hr
 1311 1299 5128 0.2533 -0.0049
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 2
O04
 72
hr
 1311 1267 5100 0.2484 -0.0176
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 3
O04
 72
hr
 1311 1280 5010 0.2555 -0.0126
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 1
O03
 72
hr
 1311 1150 4870 0.2361 -0.0672
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 2
O03
 72
hr
 1311 1074 4961 0.2165 -0.0989
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 3
O03
 72
hr
 1311 1133 4973 0.2278 -0.0733
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 1
O03
 72
hr
 1311 1285 5128 0.2506 -0.0104
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 2
O03
 72
hr
 1311 1080 5100 0.2118 -0.0945
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 3
O03
 72
hr
 1311 1163 5010 0.2321 -0.0603
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 1
O02
 72
hr
 1311 878 4870 0.1803 -0.1911
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 2
O02
 72
hr
 1311 988 4961 0.1991 -0.1373
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 3
O02
 72
hr
 1311 756 4973 0.1520 -0.2492
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 1
O02
 72
hr
 1311 939 5128 0.1831 -0.1563
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 2
O02
 72
hr
 1311 975 5100 0.1912 -0.1405
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 3
O02
 72
hr
 1311 871 5010 0.1738 -0.1908
MDA-MB-231 Geldanamycin
10
uM
LJP6
 1
O01
 72
hr
 1311 749 4870 0.1538 -0.2563
MDA-MB-231 Geldanamycin
10
uM
LJP6
 2
O01
 72
hr
 1311 958 4961 0.1931 -0.1510
MDA-MB-231 Geldanamycin
10
uM
LJP6
 3
O01
 72
hr
 1311 686 4973 0.1379 -0.2862
MDA-MB-231 Geldanamycin
10
uM
LJP5
 1
O01
 72
hr
 1311 860 5128 0.1677 -0.1932