LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PD0325901
1.11
uM
LJP6
 3
E03
 72
hr
 1311 1666 4973 0.3350 0.1324
MDA-MB-231 PD0325901
1.11
uM
LJP5
 1
C03
 72
hr
 1311 1898 5128 0.3701 0.2066
MDA-MB-231 PD0325901
1.11
uM
LJP5
 2
C03
 72
hr
 1311 1733 5100 0.3398 0.1528
MDA-MB-231 PD0325901
1.11
uM
LJP5
 3
C03
 72
hr
 1311 1494 5010 0.2982 0.0696
MDA-MB-231 PD0325901
3.33
uM
LJP6
 1
E02
 72
hr
 1311 1361 4870 0.2795 0.0197
MDA-MB-231 PD0325901
3.33
uM
LJP6
 2
E02
 72
hr
 1311 1274 4961 0.2568 -0.0151
MDA-MB-231 PD0325901
3.33
uM
LJP6
 3
E02
 72
hr
 1311 1193 4973 0.2399 -0.0481
MDA-MB-231 PD0325901
3.33
uM
LJP5
 1
C02
 72
hr
 1311 1625 5128 0.3169 0.1150
MDA-MB-231 PD0325901
3.33
uM
LJP5
 2
C02
 72
hr
 1311 1414 5100 0.2773 0.0391
MDA-MB-231 PD0325901
3.33
uM
LJP5
 3
C02
 72
hr
 1311 1443 5010 0.2880 0.0506
MDA-MB-231 PD0325901
10
uM
LJP6
 1
E01
 72
hr
 1311 1328 4870 0.2727 0.0065
MDA-MB-231 PD0325901
10
uM
LJP6
 2
E01
 72
hr
 1311 1288 4961 0.2596 -0.0095
MDA-MB-231 PD0325901
10
uM
LJP6
 3
E01
 72
hr
 1311 1022 4973 0.2055 -0.1217
MDA-MB-231 PD0325901
10
uM
LJP5
 1
C01
 72
hr
 1311 1390 5128 0.2710 0.0299
MDA-MB-231 PD0325901
10
uM
LJP5
 2
C01
 72
hr
 1311 1149 5100 0.2253 -0.0654
MDA-MB-231 PD0325901
10
uM
LJP5
 3
C01
 72
hr
 1311 1250 5010 0.2495 -0.0246
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 1
O06
 72
hr
 1311 3438 4870 0.7059 0.6639
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 2
O06
 72
hr
 1311 3400 4961 0.6853 0.6425
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 3
O06
 72
hr
 1311 3453 4973 0.6942 0.6543
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 1
O06
 72
hr
 1311 4272 5128 0.8330 0.8226
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 2
O06
 72
hr
 1311 3376 5100 0.6620 0.6202
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 3
O06
 72
hr
 1311 3546 5010 0.7077 0.6725
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 1
O05
 72
hr
 1311 1309 4870 0.2688 -0.0011
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 2
O05
 72
hr
 1311 1766 4961 0.3559 0.1676
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 3
O05
 72
hr
 1311 1488 4973 0.2992 0.0678