LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 1 | K22 | 72 | hr | 1235 | 1157 | 4119 | 0.2809 | -0.0370 |
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 2 | K22 | 72 | hr | 1235 | 1131 | 4356 | 0.2596 | -0.0474 |
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 3 | K22 | 72 | hr | 1235 | 1055 | 4326 | 0.2439 | -0.0836 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 1 | K21 | 72 | hr | 1235 | 1248 | 4119 | 0.3030 | 0.0059 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 2 | K21 | 72 | hr | 1235 | 1296 | 4356 | 0.2975 | 0.0267 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 3 | K21 | 72 | hr | 1235 | 1214 | 4326 | 0.2806 | -0.0096 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 1 | K20 | 72 | hr | 1235 | 1120 | 4119 | 0.2719 | -0.0549 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 2 | K20 | 72 | hr | 1235 | 1203 | 4356 | 0.2762 | -0.0145 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 3 | K20 | 72 | hr | 1235 | 1179 | 4326 | 0.2725 | -0.0255 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 1 | K19 | 72 | hr | 1235 | 967 | 4119 | 0.2348 | -0.1315 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 2 | K19 | 72 | hr | 1235 | 1214 | 4356 | 0.2787 | -0.0096 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 3 | K19 | 72 | hr | 1235 | 1129 | 4326 | 0.2610 | -0.0486 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 1 | C24 | 72 | hr | 1235 | 1106 | 3974 | 0.2783 | -0.0635 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 2 | C24 | 72 | hr | 1235 | 1223 | 4070 | 0.3005 | -0.0058 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 3 | C24 | 72 | hr | 1235 | 1182 | 4126 | 0.2865 | -0.0251 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 1 | C24 | 72 | hr | 1235 | 1271 | 4119 | 0.3086 | 0.0165 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 2 | C24 | 72 | hr | 1235 | 1302 | 4356 | 0.2989 | 0.0293 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 3 | C24 | 72 | hr | 1235 | 1569 | 4326 | 0.3627 | 0.1413 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 1 | C23 | 72 | hr | 1235 | 1133 | 3974 | 0.2851 | -0.0500 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 2 | C23 | 72 | hr | 1235 | 1121 | 4070 | 0.2754 | -0.0549 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 3 | C23 | 72 | hr | 1235 | 1215 | 4126 | 0.2945 | -0.0095 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 1 | C23 | 72 | hr | 1235 | 1330 | 4119 | 0.3229 | 0.0434 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 2 | C23 | 72 | hr | 1235 | 1244 | 4356 | 0.2856 | 0.0038 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 3 | C23 | 72 | hr | 1235 | 1372 | 4326 | 0.3171 | 0.0597 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 1 | C22 | 72 | hr | 1235 | 1402 | 3974 | 0.3528 | 0.0779 |