LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Foretinib | 0.37 | uM | LJP5 | 3 | H10 | 72 | hr | 1235 | 1477 | 4326 | 0.3414 | 0.1038 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 1 | H09 | 72 | hr | 1235 | 1313 | 4119 | 0.3188 | 0.0357 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 2 | H09 | 72 | hr | 1235 | 1433 | 4356 | 0.3290 | 0.0850 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 3 | H09 | 72 | hr | 1235 | 1491 | 4326 | 0.3446 | 0.1096 |
| MCF7 | Foretinib | 3.33 | uM | LJP5 | 1 | H08 | 72 | hr | 1235 | 1135 | 4119 | 0.2755 | -0.0476 |
| MCF7 | Foretinib | 3.33 | uM | LJP5 | 2 | H08 | 72 | hr | 1235 | 1335 | 4356 | 0.3065 | 0.0436 |
| MCF7 | Foretinib | 3.33 | uM | LJP5 | 3 | H08 | 72 | hr | 1235 | 1402 | 4326 | 0.3241 | 0.0725 |
| MCF7 | Foretinib | 10 | uM | LJP5 | 1 | H07 | 72 | hr | 1235 | 718 | 4119 | 0.1743 | -0.2683 |
| MCF7 | Foretinib | 10 | uM | LJP5 | 2 | H07 | 72 | hr | 1235 | 904 | 4356 | 0.2075 | -0.1578 |
| MCF7 | Foretinib | 10 | uM | LJP5 | 3 | H07 | 72 | hr | 1235 | 897 | 4326 | 0.2073 | -0.1622 |
| MCF7 | AZD 5438 | 0.04 | uM | LJP6 | 1 | J06 | 72 | hr | 1235 | 3524 | 3974 | 0.8867 | 0.8623 |
| MCF7 | AZD 5438 | 0.04 | uM | LJP6 | 2 | J06 | 72 | hr | 1235 | 3373 | 4070 | 0.8287 | 0.7930 |
| MCF7 | AZD 5438 | 0.04 | uM | LJP6 | 3 | J06 | 72 | hr | 1235 | 3812 | 4126 | 0.9238 | 0.9110 |
| MCF7 | AZD 5438 | 0.12 | uM | LJP6 | 1 | J05 | 72 | hr | 1235 | 2096 | 3974 | 0.5274 | 0.3684 |
| MCF7 | AZD 5438 | 0.12 | uM | LJP6 | 2 | J05 | 72 | hr | 1235 | 2193 | 4070 | 0.5388 | 0.3960 |
| MCF7 | AZD 5438 | 0.12 | uM | LJP6 | 3 | J05 | 72 | hr | 1235 | 2116 | 4126 | 0.5128 | 0.3625 |
| MCF7 | AZD 5438 | 0.37 | uM | LJP6 | 1 | J04 | 72 | hr | 1235 | 1439 | 3974 | 0.3621 | 0.0947 |
| MCF7 | AZD 5438 | 0.37 | uM | LJP6 | 2 | J04 | 72 | hr | 1235 | 1412 | 4070 | 0.3469 | 0.0808 |
| MCF7 | AZD 5438 | 0.37 | uM | LJP6 | 3 | J04 | 72 | hr | 1235 | 1186 | 4126 | 0.2874 | -0.0232 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 1 | J03 | 72 | hr | 1235 | 1223 | 3974 | 0.3077 | -0.0060 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 2 | J03 | 72 | hr | 1235 | 1145 | 4070 | 0.2813 | -0.0432 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 3 | J03 | 72 | hr | 1235 | 1208 | 4126 | 0.2928 | -0.0128 |
| MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 1 | J02 | 72 | hr | 1235 | 827 | 3974 | 0.2081 | -0.2119 |
| MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 2 | J02 | 72 | hr | 1235 | 760 | 4070 | 0.1867 | -0.2460 |
| MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 3 | J02 | 72 | hr | 1235 | 750 | 4126 | 0.1818 | -0.2494 |