LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A GDC-0980
0.04
uM
LJP5
 2
K24
 72
hr
 513 5455 10349 0.5271 0.7252
MCF 10A GDC-0980
0.04
uM
LJP5
 3
K24
 72
hr
 513 4579 10483 0.4368 0.6534
MCF 10A GDC-0980
0.12
uM
LJP5
 1
K23
 72
hr
 513 2056 10254 0.2005 0.3788
MCF 10A GDC-0980
0.12
uM
LJP5
 2
K23
 72
hr
 513 2652 10349 0.2562 0.4607
MCF 10A GDC-0980
0.12
uM
LJP5
 3
K23
 72
hr
 513 2615 10483 0.2494 0.4537
MCF 10A GDC-0980
0.37
uM
LJP5
 1
K22
 72
hr
 513 887 10254 0.0865 0.1349
MCF 10A GDC-0980
0.37
uM
LJP5
 2
K22
 72
hr
 513 954 10349 0.0922 0.1537
MCF 10A GDC-0980
0.37
uM
LJP5
 3
K22
 72
hr
 513 1060 10483 0.1011 0.1813
MCF 10A GDC-0980
1.11
uM
LJP5
 1
K21
 72
hr
 513 518 10254 0.0505 0.0021
MCF 10A GDC-0980
1.11
uM
LJP5
 2
K21
 72
hr
 513 750 10349 0.0725 0.0914
MCF 10A GDC-0980
1.11
uM
LJP5
 3
K21
 72
hr
 513 657 10483 0.0627 0.0583
MCF 10A GDC-0980
3.33
uM
LJP5
 1
K20
 72
hr
 513 607 10254 0.0592 0.0395
MCF 10A GDC-0980
3.33
uM
LJP5
 2
K20
 72
hr
 513 576 10349 0.0557 0.0269
MCF 10A GDC-0980
3.33
uM
LJP5
 3
K20
 72
hr
 513 628 10483 0.0599 0.0474
MCF 10A GDC-0980
10
uM
LJP5
 1
K19
 72
hr
 513 562 10254 0.0548 0.0212
MCF 10A GDC-0980
10
uM
LJP5
 2
K19
 72
hr
 513 659 10349 0.0637 0.0593
MCF 10A GDC-0980
10
uM
LJP5
 3
K19
 72
hr
 513 495 10483 0.0472 -0.0083
MCF 10A Mitoxantrone
0.04
uM
LJP6
 1
C24
 72
hr
 513 880 10537 0.0835 0.1316
MCF 10A Mitoxantrone
0.04
uM
LJP6
 2
C24
 72
hr
 513 952 10386 0.0917 0.1530
MCF 10A Mitoxantrone
0.04
uM
LJP6
 3
C24
 72
hr
 513 891 10494 0.0849 0.1350
MCF 10A Mitoxantrone
0.04
uM
LJP5
 1
C24
 72
hr
 513 1044 10254 0.1018 0.1786
MCF 10A Mitoxantrone
0.04
uM
LJP5
 2
C24
 72
hr
 513 1045 10349 0.1010 0.1782
MCF 10A Mitoxantrone
0.04
uM
LJP5
 3
C24
 72
hr
 513 1020 10483 0.0973 0.1709
MCF 10A Mitoxantrone
0.12
uM
LJP6
 1
C23
 72
hr
 513 622 10537 0.0590 0.0450
MCF 10A Mitoxantrone
0.12
uM
LJP6
 2
C23
 72
hr
 513 663 10386 0.0638 0.0607