LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Dactolisib
3.33
uM
LJP5
 1
M14
 72
hr
 513 962 10254 0.0938 0.1565
MCF 10A Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 513 1057 10349 0.1021 0.1814
MCF 10A Dactolisib
3.33
uM
LJP5
 3
M14
 72
hr
 513 884 10483 0.0843 0.1330
MCF 10A Dactolisib
10
uM
LJP5
 1
M13
 72
hr
 513 1163 10254 0.1134 0.2084
MCF 10A Dactolisib
10
uM
LJP5
 2
M13
 72
hr
 513 1159 10349 0.1120 0.2067
MCF 10A Dactolisib
10
uM
LJP5
 3
M13
 72
hr
 513 1149 10483 0.1096 0.2034
MCF 10A Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 513 9579 10254 0.9341 0.9687
MCF 10A Alpelisib
0.04
uM
LJP5
 2
N06
 72
hr
 513 9522 10349 0.9200 0.9619
MCF 10A Alpelisib
0.04
uM
LJP5
 3
N06
 72
hr
 513 9264 10483 0.8837 0.9440
MCF 10A Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 513 8309 10254 0.8103 0.9049
MCF 10A Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 513 8432 10349 0.8147 0.9076
MCF 10A Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 513 8669 10483 0.8269 0.9145
MCF 10A Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 513 7029 10254 0.6854 0.8326
MCF 10A Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 513 7354 10349 0.7106 0.8484
MCF 10A Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 513 7138 10483 0.6809 0.8309
MCF 10A Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 513 6256 10254 0.6101 0.7838
MCF 10A Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 513 7467 10349 0.7215 0.8549
MCF 10A Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 513 5816 10483 0.5548 0.7468
MCF 10A Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 513 4228 10254 0.4123 0.6292
MCF 10A Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 513 5361 10349 0.5180 0.7183
MCF 10A Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 513 4068 10483 0.3880 0.6090
MCF 10A Alpelisib
10
uM
LJP5
 1
N01
 72
hr
 513 1485 10254 0.1448 0.2787
MCF 10A Alpelisib
10
uM
LJP5
 2
N01
 72
hr
 513 1520 10349 0.1469 0.2847
MCF 10A Alpelisib
10
uM
LJP5
 3
N01
 72
hr
 513 1545 10483 0.1474 0.2881
MCF 10A GDC-0980
0.04
uM
LJP5
 1
K24
 72
hr
 513 5153 10254 0.5025 0.7055