LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A AZD 5438
1.11
uM
LJP6
 2
J03
 72
hr
 513 537 10386 0.0517 0.0104
MCF 10A AZD 5438
1.11
uM
LJP6
 3
J03
 72
hr
 513 593 10494 0.0565 0.0337
MCF 10A AZD 5438
3.33
uM
LJP6
 1
J02
 72
hr
 513 728 10537 0.0691 0.0834
MCF 10A AZD 5438
3.33
uM
LJP6
 2
J02
 72
hr
 513 653 10386 0.0629 0.0570
MCF 10A AZD 5438
3.33
uM
LJP6
 3
J02
 72
hr
 513 731 10494 0.0697 0.0846
MCF 10A AZD 5438
10
uM
LJP6
 1
J01
 72
hr
 513 593 10537 0.0563 0.0336
MCF 10A AZD 5438
10
uM
LJP6
 2
J01
 72
hr
 513 581 10386 0.0559 0.0289
MCF 10A AZD 5438
10
uM
LJP6
 3
J01
 72
hr
 513 555 10494 0.0529 0.0181
MCF 10A Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 513 2065 10254 0.2014 0.3801
MCF 10A Pelitinib
0.04
uM
LJP5
 2
I18
 72
hr
 513 2515 10349 0.2430 0.4430
MCF 10A Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 513 1818 10483 0.1734 0.3372
MCF 10A Pelitinib
0.12
uM
LJP5
 1
I17
 72
hr
 513 760 10254 0.0741 0.0951
MCF 10A Pelitinib
0.12
uM
LJP5
 2
I17
 72
hr
 513 878 10349 0.0848 0.1318
MCF 10A Pelitinib
0.12
uM
LJP5
 3
I17
 72
hr
 513 797 10483 0.0760 0.1064
MCF 10A Pelitinib
0.37
uM
LJP5
 1
I16
 72
hr
 513 684 10254 0.0667 0.0687
MCF 10A Pelitinib
0.37
uM
LJP5
 2
I16
 72
hr
 513 795 10349 0.0768 0.1062
MCF 10A Pelitinib
0.37
uM
LJP5
 3
I16
 72
hr
 513 695 10483 0.0663 0.0721
MCF 10A Pelitinib
1.11
uM
LJP5
 1
I15
 72
hr
 513 752 10254 0.0733 0.0924
MCF 10A Pelitinib
1.11
uM
LJP5
 2
I15
 72
hr
 513 808 10349 0.0781 0.1103
MCF 10A Pelitinib
1.11
uM
LJP5
 3
I15
 72
hr
 513 741 10483 0.0707 0.0880
MCF 10A Pelitinib
3.33
uM
LJP5
 1
I14
 72
hr
 513 579 10254 0.0565 0.0282
MCF 10A Pelitinib
3.33
uM
LJP5
 2
I14
 72
hr
 513 795 10349 0.0768 0.1062
MCF 10A Pelitinib
3.33
uM
LJP5
 3
I14
 72
hr
 513 666 10483 0.0635 0.0616
MCF 10A Pelitinib
10
uM
LJP5
 1
I13
 72
hr
 513 529 10254 0.0516 0.0070
MCF 10A Pelitinib
10
uM
LJP5
 2
I13
 72
hr
 513 556 10349 0.0537 0.0186