LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Y39983 | 3.33 | uM | LJP6 | 3 | P02 | 72 | hr | 513 | 5578 | 10494 | 0.5315 | 0.7297 |
| MCF 10A | Y39983 | 10 | uM | LJP6 | 1 | P01 | 72 | hr | 513 | 1118 | 10537 | 0.1061 | 0.1955 |
| MCF 10A | Y39983 | 10 | uM | LJP6 | 2 | P01 | 72 | hr | 513 | 1054 | 10386 | 0.1015 | 0.1803 |
| MCF 10A | Y39983 | 10 | uM | LJP6 | 3 | P01 | 72 | hr | 513 | 1228 | 10494 | 0.1170 | 0.2218 |
| MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 1 | H06 | 72 | hr | 513 | 11473 | 10537 | 1.0887 | 1.0394 |
| MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 2 | H06 | 72 | hr | 513 | 10816 | 10386 | 1.0413 | 1.0188 |
| MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 3 | H06 | 72 | hr | 513 | 10340 | 10494 | 0.9853 | 0.9932 |
| MCF 10A | Nintedanib | 0.12 | uM | LJP6 | 1 | H05 | 72 | hr | 513 | 10742 | 10537 | 1.0194 | 1.0088 |
| MCF 10A | Nintedanib | 0.12 | uM | LJP6 | 2 | H05 | 72 | hr | 513 | 10063 | 10386 | 0.9688 | 0.9855 |
| MCF 10A | Nintedanib | 0.12 | uM | LJP6 | 3 | H05 | 72 | hr | 513 | 10297 | 10494 | 0.9812 | 0.9913 |
| MCF 10A | Nintedanib | 0.37 | uM | LJP6 | 1 | H04 | 72 | hr | 513 | 10714 | 10537 | 1.0167 | 1.0076 |
| MCF 10A | Nintedanib | 0.37 | uM | LJP6 | 2 | H04 | 72 | hr | 513 | 10322 | 10386 | 0.9938 | 0.9971 |
| MCF 10A | Nintedanib | 0.37 | uM | LJP6 | 3 | H04 | 72 | hr | 513 | 10136 | 10494 | 0.9658 | 0.9841 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 1 | H03 | 72 | hr | 513 | 10802 | 10537 | 1.0251 | 1.0114 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 2 | H03 | 72 | hr | 513 | 10380 | 10386 | 0.9993 | 0.9997 |
| MCF 10A | Nintedanib | 1.11 | uM | LJP6 | 3 | H03 | 72 | hr | 513 | 10195 | 10494 | 0.9714 | 0.9867 |
| MCF 10A | Nintedanib | 3.33 | uM | LJP6 | 1 | H02 | 72 | hr | 513 | 8225 | 10537 | 0.7805 | 0.8895 |
| MCF 10A | Nintedanib | 3.33 | uM | LJP6 | 2 | H02 | 72 | hr | 513 | 7858 | 10386 | 0.7565 | 0.8754 |
| MCF 10A | Nintedanib | 3.33 | uM | LJP6 | 3 | H02 | 72 | hr | 513 | 7795 | 10494 | 0.7428 | 0.8679 |
| MCF 10A | Nintedanib | 10 | uM | LJP6 | 1 | H01 | 72 | hr | 513 | 9271 | 10537 | 0.8798 | 0.9421 |
| MCF 10A | Nintedanib | 10 | uM | LJP6 | 2 | H01 | 72 | hr | 513 | 8903 | 10386 | 0.8571 | 0.9302 |
| MCF 10A | Nintedanib | 10 | uM | LJP6 | 3 | H01 | 72 | hr | 513 | 8948 | 10494 | 0.8526 | 0.9281 |
| MCF 10A | Foretinib | 0.04 | uM | LJP5 | 1 | H12 | 72 | hr | 513 | 10792 | 10254 | 1.0524 | 1.0238 |
| MCF 10A | Foretinib | 0.04 | uM | LJP5 | 2 | H12 | 72 | hr | 513 | 11240 | 10349 | 1.0860 | 1.0385 |
| MCF 10A | Foretinib | 0.04 | uM | LJP5 | 3 | H12 | 72 | hr | 513 | 11369 | 10483 | 1.0845 | 1.0376 |