LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Palbociclib | 1.11 | uM | LJP6 | 3 | E15 | 72 | hr | 1235 | 1838 | 4126 | 0.4454 | 0.2565 |
| MCF7 | Palbociclib | 3.33 | uM | LJP6 | 1 | E14 | 72 | hr | 1235 | 1888 | 3974 | 0.4751 | 0.2861 |
| MCF7 | Palbociclib | 3.33 | uM | LJP6 | 2 | E14 | 72 | hr | 1235 | 2024 | 4070 | 0.4973 | 0.3324 |
| MCF7 | Palbociclib | 3.33 | uM | LJP6 | 3 | E14 | 72 | hr | 1235 | 1887 | 4126 | 0.4573 | 0.2757 |
| MCF7 | Palbociclib | 10 | uM | LJP6 | 1 | E13 | 72 | hr | 1235 | 1921 | 3974 | 0.4834 | 0.2994 |
| MCF7 | Palbociclib | 10 | uM | LJP6 | 2 | E13 | 72 | hr | 1235 | 1953 | 4070 | 0.4798 | 0.3051 |
| MCF7 | Palbociclib | 10 | uM | LJP6 | 3 | E13 | 72 | hr | 1235 | 2026 | 4126 | 0.4910 | 0.3289 |
| MCF7 | PF562271 | 0.04 | uM | LJP6 | 1 | F18 | 72 | hr | 1235 | 3365 | 3974 | 0.8467 | 0.8120 |
| MCF7 | PF562271 | 0.04 | uM | LJP6 | 2 | F18 | 72 | hr | 1235 | 3794 | 4070 | 0.9321 | 0.9199 |
| MCF7 | PF562271 | 0.04 | uM | LJP6 | 3 | F18 | 72 | hr | 1235 | 3562 | 4126 | 0.8632 | 0.8379 |
| MCF7 | PF562271 | 0.12 | uM | LJP6 | 1 | F17 | 72 | hr | 1235 | 3352 | 3974 | 0.8435 | 0.8079 |
| MCF7 | PF562271 | 0.12 | uM | LJP6 | 2 | F17 | 72 | hr | 1235 | 3401 | 4070 | 0.8356 | 0.8017 |
| MCF7 | PF562271 | 0.12 | uM | LJP6 | 3 | F17 | 72 | hr | 1235 | 3257 | 4126 | 0.7893 | 0.7457 |
| MCF7 | PF562271 | 0.37 | uM | LJP6 | 1 | F16 | 72 | hr | 1235 | 2454 | 3974 | 0.6175 | 0.5025 |
| MCF7 | PF562271 | 0.37 | uM | LJP6 | 2 | F16 | 72 | hr | 1235 | 2560 | 4070 | 0.6289 | 0.5274 |
| MCF7 | PF562271 | 0.37 | uM | LJP6 | 3 | F16 | 72 | hr | 1235 | 2241 | 4126 | 0.5431 | 0.4082 |
| MCF7 | PF562271 | 1.11 | uM | LJP6 | 1 | F15 | 72 | hr | 1235 | 1520 | 3974 | 0.3825 | 0.1309 |
| MCF7 | PF562271 | 1.11 | uM | LJP6 | 2 | F15 | 72 | hr | 1235 | 1763 | 4070 | 0.4331 | 0.2297 |
| MCF7 | PF562271 | 1.11 | uM | LJP6 | 3 | F15 | 72 | hr | 1235 | 1490 | 4126 | 0.3611 | 0.1137 |
| MCF7 | PF562271 | 3.33 | uM | LJP6 | 1 | F14 | 72 | hr | 1235 | 964 | 3974 | 0.2426 | -0.1368 |
| MCF7 | PF562271 | 3.33 | uM | LJP6 | 2 | F14 | 72 | hr | 1235 | 956 | 4070 | 0.2349 | -0.1385 |
| MCF7 | PF562271 | 3.33 | uM | LJP6 | 3 | F14 | 72 | hr | 1235 | 1038 | 4126 | 0.2516 | -0.0952 |
| MCF7 | PF562271 | 10 | uM | LJP6 | 1 | F13 | 72 | hr | 1235 | 703 | 3974 | 0.1769 | -0.2843 |
| MCF7 | PF562271 | 10 | uM | LJP6 | 2 | F13 | 72 | hr | 1235 | 786 | 4070 | 0.1931 | -0.2312 |
| MCF7 | PF562271 | 10 | uM | LJP6 | 3 | F13 | 72 | hr | 1235 | 686 | 4126 | 0.1663 | -0.2869 |