LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 1 | N15 | 72 | hr | 1235 | 3657 | 4119 | 0.8878 | 0.8676 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 2 | N15 | 72 | hr | 1235 | 4267 | 4356 | 0.9795 | 0.9774 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 3 | N15 | 72 | hr | 1235 | 4516 | 4326 | 1.0438 | 1.0480 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 1 | N14 | 72 | hr | 1235 | 3983 | 4119 | 0.9669 | 0.9617 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 2 | N14 | 72 | hr | 1235 | 4674 | 4356 | 1.0729 | 1.0790 |
| MCF7 | Nilotinib | 3.33 | uM | LJP5 | 3 | N14 | 72 | hr | 1235 | 4392 | 4326 | 1.0152 | 1.0167 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 1 | N13 | 72 | hr | 1235 | 1724 | 4119 | 0.4185 | 0.2115 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 2 | N13 | 72 | hr | 1235 | 1460 | 4356 | 0.3352 | 0.0962 |
| MCF7 | Nilotinib | 10 | uM | LJP5 | 3 | N13 | 72 | hr | 1235 | 1716 | 4326 | 0.3966 | 0.1993 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 1 | K24 | 72 | hr | 1235 | 2764 | 3974 | 0.6955 | 0.6124 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 2 | K24 | 72 | hr | 1235 | 3000 | 4070 | 0.7370 | 0.6749 |
| MCF7 | JNK-9L | 0.04 | uM | LJP6 | 3 | K24 | 72 | hr | 1235 | 2519 | 4126 | 0.6105 | 0.5061 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 1 | K23 | 72 | hr | 1235 | 2158 | 3974 | 0.5430 | 0.3922 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 2 | K23 | 72 | hr | 1235 | 2160 | 4070 | 0.5307 | 0.3838 |
| MCF7 | JNK-9L | 0.12 | uM | LJP6 | 3 | K23 | 72 | hr | 1235 | 1977 | 4126 | 0.4791 | 0.3103 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 1 | K22 | 72 | hr | 1235 | 1331 | 3974 | 0.3349 | 0.0452 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 2 | K22 | 72 | hr | 1235 | 1464 | 4070 | 0.3597 | 0.1037 |
| MCF7 | JNK-9L | 0.37 | uM | LJP6 | 3 | K22 | 72 | hr | 1235 | 1315 | 4126 | 0.3187 | 0.0365 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 1 | K21 | 72 | hr | 1235 | 1082 | 3974 | 0.2723 | -0.0756 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 2 | K21 | 72 | hr | 1235 | 1025 | 4070 | 0.2518 | -0.1029 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 3 | K21 | 72 | hr | 1235 | 841 | 4126 | 0.2038 | -0.1983 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 1 | K20 | 72 | hr | 1235 | 1072 | 3974 | 0.2697 | -0.0807 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 2 | K20 | 72 | hr | 1235 | 1068 | 4070 | 0.2624 | -0.0812 |
| MCF7 | JNK-9L | 3.33 | uM | LJP6 | 3 | K20 | 72 | hr | 1235 | 1052 | 4126 | 0.2550 | -0.0882 |
| MCF7 | JNK-9L | 10 | uM | LJP6 | 1 | K19 | 72 | hr | 1235 | 922 | 3974 | 0.2320 | -0.1594 |