LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3 XMD16-144
3.33
uM
LJP5
1
M08
72
hr
1476 1640 3788 0.4329 0.0802
SK-BR-3 XMD16-144
3.33
uM
LJP5
2
M08
72
hr
1476 1475 3731 0.3953 -0.0009
SK-BR-3 XMD16-144
3.33
uM
LJP5
3
M08
72
hr
1476 1445 3796 0.3806 -0.0158
SK-BR-3 XMD16-144
10
uM
LJP5
1
M07
72
hr
1476 985 3788 0.2600 -0.2576
SK-BR-3 XMD16-144
10
uM
LJP5
2
M07
72
hr
1476 1088 3731 0.2916 -0.2042
SK-BR-3 XMD16-144
10
uM
LJP5
3
M07
72
hr
1476 1186 3796 0.3124 -0.1487
SK-BR-3 Erlotinib
0.04
uM
LJP5
1
M24
72
hr
1476 3297 3788 0.8702 0.8056
SK-BR-3 Erlotinib
0.04
uM
LJP5
2
M24
72
hr
1476 2957 3731 0.7925 0.6808
SK-BR-3 Erlotinib
0.04
uM
LJP5
3
M24
72
hr
1476 2840 3796 0.7480 0.6162
SK-BR-3 Erlotinib
0.12
uM
LJP5
1
M23
72
hr
1476 3439 3788 0.9077 0.8625
SK-BR-3 Erlotinib
0.12
uM
LJP5
2
M23
72
hr
1476 3273 3731 0.8772 0.8133
SK-BR-3 Erlotinib
0.12
uM
LJP5
3
M23
72
hr
1476 3240 3796 0.8534 0.7803
SK-BR-3 Erlotinib
0.37
uM
LJP5
1
M22
72
hr
1476 3586 3788 0.9465 0.9207
SK-BR-3 Erlotinib
0.37
uM
LJP5
2
M22
72
hr
1476 3211 3731 0.8606 0.7876
SK-BR-3 Erlotinib
0.37
uM
LJP5
3
M22
72
hr
1476 3479 3796 0.9163 0.8758
SK-BR-3 Erlotinib
1.11
uM
LJP5
1
M21
72
hr
1476 3445 3788 0.9093 0.8649
SK-BR-3 Erlotinib
1.11
uM
LJP5
2
M21
72
hr
1476 3237 3731 0.8676 0.7984
SK-BR-3 Erlotinib
1.11
uM
LJP5
3
M21
72
hr
1476 3337 3796 0.8789 0.8193
SK-BR-3 Erlotinib
3.33
uM
LJP5
1
M20
72
hr
1476 3294 3788 0.8694 0.8044
SK-BR-3 Erlotinib
3.33
uM
LJP5
2
M20
72
hr
1476 3152 3731 0.8448 0.7630
SK-BR-3 Erlotinib
3.33
uM
LJP5
3
M20
72
hr
1476 3402 3796 0.8961 0.8452
SK-BR-3 Erlotinib
10
uM
LJP5
1
M19
72
hr
1476 1804 3788 0.4762 0.1587
SK-BR-3 Erlotinib
10
uM
LJP5
2
M19
72
hr
1476 1857 3731 0.4977 0.1869
SK-BR-3 Erlotinib
10
uM
LJP5
3
M19
72
hr
1476 1912 3796 0.5036 0.2088
SK-BR-3 Gefitinib
0.04
uM
LJP6
1
N12
72
hr
1476 3244 3413 0.9504 0.9176