LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Barasertib | 3.33 | uM | LJP5 | 3 | D08 | 72 | hr | 1476 | 1392 | 3796 | 0.3666 | -0.0424 |
| SK-BR-3 | Barasertib | 10 | uM | LJP5 | 1 | D07 | 72 | hr | 1476 | 1363 | 3788 | 0.3598 | -0.0572 |
| SK-BR-3 | Barasertib | 10 | uM | LJP5 | 2 | D07 | 72 | hr | 1476 | 1417 | 3731 | 0.3798 | -0.0304 |
| SK-BR-3 | Barasertib | 10 | uM | LJP5 | 3 | D07 | 72 | hr | 1476 | 1316 | 3796 | 0.3466 | -0.0811 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 1 | C18 | 72 | hr | 1476 | 3766 | 3788 | 0.9940 | 0.9912 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 2 | C18 | 72 | hr | 1476 | 4051 | 3731 | 1.0857 | 1.1268 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 3 | C18 | 72 | hr | 1476 | 4186 | 3796 | 1.1026 | 1.1486 |
| SK-BR-3 | Vemurafenib | 0.12 | uM | LJP5 | 1 | C17 | 72 | hr | 1476 | 3811 | 3788 | 1.0059 | 1.0087 |
| SK-BR-3 | Vemurafenib | 0.12 | uM | LJP5 | 2 | C17 | 72 | hr | 1476 | 4021 | 3731 | 1.0777 | 1.1151 |
| SK-BR-3 | Vemurafenib | 0.12 | uM | LJP5 | 3 | C17 | 72 | hr | 1476 | 4089 | 3796 | 1.0770 | 1.1119 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 1 | C16 | 72 | hr | 1476 | 3506 | 3788 | 0.9254 | 0.8891 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 2 | C16 | 72 | hr | 1476 | 3970 | 3731 | 1.0640 | 1.0950 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 3 | C16 | 72 | hr | 1476 | 4155 | 3796 | 1.0944 | 1.1369 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 1 | C15 | 72 | hr | 1476 | 3885 | 3788 | 1.0254 | 1.0373 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 2 | C15 | 72 | hr | 1476 | 3686 | 3731 | 0.9879 | 0.9819 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 3 | C15 | 72 | hr | 1476 | 3685 | 3796 | 0.9706 | 0.9567 |
| SK-BR-3 | Vemurafenib | 3.33 | uM | LJP5 | 1 | C14 | 72 | hr | 1476 | 3616 | 3788 | 0.9544 | 0.9325 |
| SK-BR-3 | Vemurafenib | 3.33 | uM | LJP5 | 2 | C14 | 72 | hr | 1476 | 3570 | 3731 | 0.9568 | 0.9350 |
| SK-BR-3 | Vemurafenib | 3.33 | uM | LJP5 | 3 | C14 | 72 | hr | 1476 | 3814 | 3796 | 1.0046 | 1.0067 |
| SK-BR-3 | Vemurafenib | 10 | uM | LJP5 | 1 | C13 | 72 | hr | 1476 | 3311 | 3788 | 0.8739 | 0.8112 |
| SK-BR-3 | Vemurafenib | 10 | uM | LJP5 | 2 | C13 | 72 | hr | 1476 | 3088 | 3731 | 0.8276 | 0.7361 |
| SK-BR-3 | Vemurafenib | 10 | uM | LJP5 | 3 | C13 | 72 | hr | 1476 | 3201 | 3796 | 0.8431 | 0.7645 |
| SK-BR-3 | Enzastaurin | 0.04 | uM | LJP5 | 1 | D18 | 72 | hr | 1476 | 4152 | 3788 | 1.0959 | 1.1394 |
| SK-BR-3 | Enzastaurin | 0.04 | uM | LJP5 | 2 | D18 | 72 | hr | 1476 | 4409 | 3731 | 1.1817 | 1.2659 |
| SK-BR-3 | Enzastaurin | 0.04 | uM | LJP5 | 3 | D18 | 72 | hr | 1476 | 4321 | 3796 | 1.1381 | 1.1992 |