LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | BX-912 | 10 | uM | LJP5 | 1 | L19 | 72 | hr | 1476 | 1597 | 3788 | 0.4215 | 0.0593 |
| SK-BR-3 | BX-912 | 10 | uM | LJP5 | 2 | L19 | 72 | hr | 1476 | 1461 | 3731 | 0.3916 | -0.0080 |
| SK-BR-3 | BX-912 | 10 | uM | LJP5 | 3 | L19 | 72 | hr | 1476 | 1599 | 3796 | 0.4212 | 0.0601 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 1 | M12 | 72 | hr | 1476 | 3894 | 3413 | 1.1408 | 1.2303 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 2 | M12 | 72 | hr | 1476 | 4148 | 3783 | 1.0963 | 1.1402 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 3 | M12 | 72 | hr | 1476 | 3860 | 3734 | 1.0337 | 1.0502 |
| SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 1 | M11 | 72 | hr | 1476 | 3727 | 3413 | 1.0919 | 1.1509 |
| SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 2 | M11 | 72 | hr | 1476 | 3649 | 3783 | 0.9645 | 0.9474 |
| SK-BR-3 | Selumetinib | 0.12 | uM | LJP6 | 3 | M11 | 72 | hr | 1476 | 3765 | 3734 | 1.0083 | 1.0124 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 1 | M10 | 72 | hr | 1476 | 3609 | 3413 | 1.0573 | 1.0944 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 2 | M10 | 72 | hr | 1476 | 3927 | 3783 | 1.0379 | 1.0556 |
| SK-BR-3 | Selumetinib | 0.37 | uM | LJP6 | 3 | M10 | 72 | hr | 1476 | 3610 | 3734 | 0.9668 | 0.9501 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 1 | M09 | 72 | hr | 1476 | 3720 | 3413 | 1.0899 | 1.1476 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 2 | M09 | 72 | hr | 1476 | 3809 | 3783 | 1.0067 | 1.0099 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 3 | M09 | 72 | hr | 1476 | 3828 | 3734 | 1.0252 | 1.0375 |
| SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 1 | M08 | 72 | hr | 1476 | 3516 | 3413 | 1.0301 | 1.0497 |
| SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 2 | M08 | 72 | hr | 1476 | 3859 | 3783 | 1.0200 | 1.0293 |
| SK-BR-3 | Selumetinib | 3.33 | uM | LJP6 | 3 | M08 | 72 | hr | 1476 | 3606 | 3734 | 0.9657 | 0.9485 |
| SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 1 | M07 | 72 | hr | 1476 | 3238 | 3413 | 0.9487 | 0.9147 |
| SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 2 | M07 | 72 | hr | 1476 | 3641 | 3783 | 0.9623 | 0.9442 |
| SK-BR-3 | Selumetinib | 10 | uM | LJP6 | 3 | M07 | 72 | hr | 1476 | 3687 | 3734 | 0.9874 | 0.9811 |
| SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 1 | F06 | 72 | hr | 1476 | 3469 | 3413 | 1.0163 | 1.0270 |
| SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 2 | F06 | 72 | hr | 1476 | 3442 | 3783 | 0.9097 | 0.8654 |
| SK-BR-3 | MK2206 | 0.04 | uM | LJP6 | 3 | F06 | 72 | hr | 1476 | 3206 | 3734 | 0.8586 | 0.7847 |
| SK-BR-3 | MK2206 | 0.12 | uM | LJP6 | 1 | F05 | 72 | hr | 1476 | 2811 | 3413 | 0.8236 | 0.7033 |