LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | KIN001-043 | 10 | uM | LJP6 | 3 | C07 | 72 | hr | 1476 | 1711 | 3734 | 0.4582 | 0.1163 |
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 1 | D12 | 72 | hr | 1476 | 4380 | 3413 | 1.2832 | 1.4583 |
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 2 | D12 | 72 | hr | 1476 | 4019 | 3783 | 1.0622 | 1.0910 |
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 3 | D12 | 72 | hr | 1476 | 4300 | 3734 | 1.1516 | 1.2224 |
| SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 1 | D11 | 72 | hr | 1476 | 4261 | 3413 | 1.2484 | 1.4029 |
| SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 2 | D11 | 72 | hr | 1476 | 3888 | 3783 | 1.0276 | 1.0406 |
| SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 3 | D11 | 72 | hr | 1476 | 4326 | 3734 | 1.1585 | 1.2324 |
| SK-BR-3 | Saracatinib | 0.37 | uM | LJP6 | 1 | D10 | 72 | hr | 1476 | 3895 | 3413 | 1.1411 | 1.2308 |
| SK-BR-3 | Saracatinib | 0.37 | uM | LJP6 | 2 | D10 | 72 | hr | 1476 | 3884 | 3783 | 1.0266 | 1.0390 |
| SK-BR-3 | Saracatinib | 0.37 | uM | LJP6 | 3 | D10 | 72 | hr | 1476 | 3666 | 3734 | 0.9818 | 0.9727 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 1 | D09 | 72 | hr | 1476 | 3417 | 3413 | 1.0011 | 1.0018 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 2 | D09 | 72 | hr | 1476 | 3070 | 3783 | 0.8114 | 0.7146 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 3 | D09 | 72 | hr | 1476 | 3669 | 3734 | 0.9826 | 0.9739 |
| SK-BR-3 | Saracatinib | 3.33 | uM | LJP6 | 1 | D08 | 72 | hr | 1476 | 3055 | 3413 | 0.8950 | 0.8247 |
| SK-BR-3 | Saracatinib | 3.33 | uM | LJP6 | 2 | D08 | 72 | hr | 1476 | 3013 | 3783 | 0.7964 | 0.6911 |
| SK-BR-3 | Saracatinib | 3.33 | uM | LJP6 | 3 | D08 | 72 | hr | 1476 | 3029 | 3734 | 0.8112 | 0.7105 |
| SK-BR-3 | Saracatinib | 10 | uM | LJP6 | 1 | D07 | 72 | hr | 1476 | 2057 | 3413 | 0.6027 | 0.3155 |
| SK-BR-3 | Saracatinib | 10 | uM | LJP6 | 2 | D07 | 72 | hr | 1476 | 1847 | 3783 | 0.4882 | 0.1792 |
| SK-BR-3 | Saracatinib | 10 | uM | LJP6 | 3 | D07 | 72 | hr | 1476 | 2002 | 3734 | 0.5361 | 0.2553 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 1 | B24 | 72 | hr | 1476 | 2907 | 3788 | 0.7673 | 0.6459 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 2 | B24 | 72 | hr | 1476 | 2875 | 3731 | 0.7705 | 0.6458 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 3 | B24 | 72 | hr | 1476 | 2579 | 3796 | 0.6793 | 0.5057 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 1 | B23 | 72 | hr | 1476 | 3258 | 3788 | 0.8599 | 0.7899 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 2 | B23 | 72 | hr | 1476 | 2986 | 3731 | 0.8003 | 0.6931 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 3 | B23 | 72 | hr | 1476 | 2948 | 3796 | 0.7765 | 0.6610 |