LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | CGP60474 | 10 | uM | LJP6 | 3 | G01 | 72 | hr | 1476 | 610 | 3734 | 0.1634 | -0.4835 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP5 | 1 | F01 | 72 | hr | 1476 | 686 | 3788 | 0.1811 | -0.4311 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP5 | 2 | F01 | 72 | hr | 1476 | 847 | 3731 | 0.2270 | -0.3401 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP5 | 3 | F01 | 72 | hr | 1476 | 1007 | 3796 | 0.2652 | -0.2450 |
| SK-BR-3 | PD173074 | 0.04 | uM | LJP6 | 1 | I12 | 72 | hr | 1476 | 3987 | 3413 | 1.1681 | 1.2743 |
| SK-BR-3 | PD173074 | 0.04 | uM | LJP6 | 2 | I12 | 72 | hr | 1476 | 4314 | 3783 | 1.1402 | 1.2030 |
| SK-BR-3 | PD173074 | 0.04 | uM | LJP6 | 3 | I12 | 72 | hr | 1476 | 4626 | 3734 | 1.2389 | 1.3471 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 1 | I11 | 72 | hr | 1476 | 4032 | 3413 | 1.1813 | 1.2955 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 2 | I11 | 72 | hr | 1476 | 4361 | 3783 | 1.1526 | 1.2207 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 3 | I11 | 72 | hr | 1476 | 4486 | 3734 | 1.2014 | 1.2938 |
| SK-BR-3 | PD173074 | 0.37 | uM | LJP6 | 1 | I10 | 72 | hr | 1476 | 4059 | 3413 | 1.1892 | 1.3082 |
| SK-BR-3 | PD173074 | 0.37 | uM | LJP6 | 2 | I10 | 72 | hr | 1476 | 4040 | 3783 | 1.0678 | 1.0990 |
| SK-BR-3 | PD173074 | 0.37 | uM | LJP6 | 3 | I10 | 72 | hr | 1476 | 4088 | 3734 | 1.0948 | 1.1400 |
| SK-BR-3 | PD173074 | 1.11 | uM | LJP6 | 1 | I09 | 72 | hr | 1476 | 4124 | 3413 | 1.2082 | 1.3388 |
| SK-BR-3 | PD173074 | 1.11 | uM | LJP6 | 2 | I09 | 72 | hr | 1476 | 4406 | 3783 | 1.1645 | 1.2375 |
| SK-BR-3 | PD173074 | 1.11 | uM | LJP6 | 3 | I09 | 72 | hr | 1476 | 4278 | 3734 | 1.1457 | 1.2139 |
| SK-BR-3 | PD173074 | 3.33 | uM | LJP6 | 1 | I08 | 72 | hr | 1476 | 4212 | 3413 | 1.2340 | 1.3800 |
| SK-BR-3 | PD173074 | 3.33 | uM | LJP6 | 2 | I08 | 72 | hr | 1476 | 4284 | 3783 | 1.1323 | 1.1917 |
| SK-BR-3 | PD173074 | 3.33 | uM | LJP6 | 3 | I08 | 72 | hr | 1476 | 4164 | 3734 | 1.1151 | 1.1697 |
| SK-BR-3 | PD173074 | 10 | uM | LJP6 | 1 | I07 | 72 | hr | 1476 | 1960 | 3413 | 0.5742 | 0.2639 |
| SK-BR-3 | PD173074 | 10 | uM | LJP6 | 2 | I07 | 72 | hr | 1476 | 2046 | 3783 | 0.5408 | 0.2715 |
| SK-BR-3 | PD173074 | 10 | uM | LJP6 | 3 | I07 | 72 | hr | 1476 | 1934 | 3734 | 0.5179 | 0.2233 |
| SK-BR-3 | Crizotinib | 0.04 | uM | LJP5 | 1 | A24 | 72 | hr | 1476 | 2972 | 3788 | 0.7845 | 0.6729 |
| SK-BR-3 | Crizotinib | 0.04 | uM | LJP5 | 2 | A24 | 72 | hr | 1476 | 2839 | 3731 | 0.7609 | 0.6303 |
| SK-BR-3 | Crizotinib | 0.04 | uM | LJP5 | 3 | A24 | 72 | hr | 1476 | 2801 | 3796 | 0.7378 | 0.5998 |