LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 2 | M06 | 72 | hr | 1476 | 4473 | 3783 | 1.1822 | 1.2625 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 3 | M06 | 72 | hr | 1476 | 3757 | 3734 | 1.0061 | 1.0092 |
| SK-BR-3 | HG-6-64-01 | 0.12 | uM | LJP6 | 1 | M05 | 72 | hr | 1476 | 3628 | 3413 | 1.0629 | 1.1035 |
| SK-BR-3 | HG-6-64-01 | 0.12 | uM | LJP6 | 2 | M05 | 72 | hr | 1476 | 3977 | 3783 | 1.0511 | 1.0749 |
| SK-BR-3 | HG-6-64-01 | 0.12 | uM | LJP6 | 3 | M05 | 72 | hr | 1476 | 3440 | 3734 | 0.9213 | 0.8811 |
| SK-BR-3 | HG-6-64-01 | 0.37 | uM | LJP6 | 1 | M04 | 72 | hr | 1476 | 3133 | 3413 | 0.9179 | 0.8631 |
| SK-BR-3 | HG-6-64-01 | 0.37 | uM | LJP6 | 2 | M04 | 72 | hr | 1476 | 3388 | 3783 | 0.8955 | 0.8438 |
| SK-BR-3 | HG-6-64-01 | 0.37 | uM | LJP6 | 3 | M04 | 72 | hr | 1476 | 3237 | 3734 | 0.8669 | 0.7975 |
| SK-BR-3 | HG-6-64-01 | 1.11 | uM | LJP6 | 1 | M03 | 72 | hr | 1476 | 2780 | 3413 | 0.8145 | 0.6877 |
| SK-BR-3 | HG-6-64-01 | 1.11 | uM | LJP6 | 2 | M03 | 72 | hr | 1476 | 2768 | 3783 | 0.7316 | 0.5887 |
| SK-BR-3 | HG-6-64-01 | 1.11 | uM | LJP6 | 3 | M03 | 72 | hr | 1476 | 2843 | 3734 | 0.7614 | 0.6314 |
| SK-BR-3 | HG-6-64-01 | 3.33 | uM | LJP6 | 1 | M02 | 72 | hr | 1476 | 2153 | 3413 | 0.6308 | 0.3661 |
| SK-BR-3 | HG-6-64-01 | 3.33 | uM | LJP6 | 2 | M02 | 72 | hr | 1476 | 2035 | 3783 | 0.5379 | 0.2665 |
| SK-BR-3 | HG-6-64-01 | 3.33 | uM | LJP6 | 3 | M02 | 72 | hr | 1476 | 1877 | 3734 | 0.5027 | 0.1963 |
| SK-BR-3 | HG-6-64-01 | 10 | uM | LJP6 | 1 | M01 | 72 | hr | 1476 | 877 | 3413 | 0.2569 | -0.3502 |
| SK-BR-3 | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 1476 | 854 | 3783 | 0.2257 | -0.3320 |
| SK-BR-3 | HG-6-64-01 | 10 | uM | LJP6 | 3 | M01 | 72 | hr | 1476 | 698 | 3734 | 0.1869 | -0.4287 |
| SK-BR-3 | Neratinib | 0.04 | uM | LJP5 | 1 | A18 | 72 | hr | 1476 | 1492 | 3788 | 0.3938 | 0.0076 |
| SK-BR-3 | Neratinib | 0.04 | uM | LJP5 | 2 | A18 | 72 | hr | 1476 | 1262 | 3731 | 0.3382 | -0.1109 |
| SK-BR-3 | Neratinib | 0.04 | uM | LJP5 | 3 | A18 | 72 | hr | 1476 | 1292 | 3796 | 0.3403 | -0.0934 |
| SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 1 | A17 | 72 | hr | 1476 | 1405 | 3788 | 0.3709 | -0.0360 |
| SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 2 | A17 | 72 | hr | 1476 | 1349 | 3731 | 0.3615 | -0.0654 |
| SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 3 | A17 | 72 | hr | 1476 | 1370 | 3796 | 0.3609 | -0.0536 |
| SK-BR-3 | Neratinib | 0.37 | uM | LJP5 | 1 | A16 | 72 | hr | 1476 | 1432 | 3788 | 0.3780 | -0.0224 |
| SK-BR-3 | Neratinib | 0.37 | uM | LJP5 | 2 | A16 | 72 | hr | 1476 | 1346 | 3731 | 0.3607 | -0.0670 |