LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 2 | C22 | 72 | hr | 1235 | 1301 | 4070 | 0.3196 | 0.0305 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 3 | C22 | 72 | hr | 1235 | 1186 | 4126 | 0.2874 | -0.0232 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP5 | 1 | C22 | 72 | hr | 1235 | 1454 | 4119 | 0.3530 | 0.0983 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP5 | 2 | C22 | 72 | hr | 1235 | 1435 | 4356 | 0.3294 | 0.0859 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP5 | 3 | C22 | 72 | hr | 1235 | 1574 | 4326 | 0.3638 | 0.1434 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 1 | C21 | 72 | hr | 1235 | 1022 | 3974 | 0.2572 | -0.1064 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 2 | C21 | 72 | hr | 1235 | 986 | 4070 | 0.2422 | -0.1229 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 3 | C21 | 72 | hr | 1235 | 956 | 4126 | 0.2317 | -0.1370 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP5 | 1 | C21 | 72 | hr | 1235 | 1027 | 4119 | 0.2493 | -0.1009 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP5 | 2 | C21 | 72 | hr | 1235 | 1058 | 4356 | 0.2429 | -0.0817 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP5 | 3 | C21 | 72 | hr | 1235 | 1099 | 4326 | 0.2540 | -0.0626 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 1 | C20 | 72 | hr | 1235 | 593 | 3974 | 0.1492 | -0.3530 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 2 | C20 | 72 | hr | 1235 | 717 | 4070 | 0.1762 | -0.2711 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 3 | C20 | 72 | hr | 1235 | 671 | 4126 | 0.1626 | -0.2959 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 1 | C20 | 72 | hr | 1235 | 642 | 4119 | 0.1559 | -0.3139 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 2 | C20 | 72 | hr | 1235 | 587 | 4356 | 0.1348 | -0.3359 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 3 | C20 | 72 | hr | 1235 | 636 | 4326 | 0.1470 | -0.3073 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1235 | 446 | 3974 | 0.1122 | -0.4536 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1235 | 344 | 4070 | 0.0845 | -0.5244 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1235 | 434 | 4126 | 0.1052 | -0.4519 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 1235 | 455 | 4119 | 0.1105 | -0.4372 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1235 | 474 | 4356 | 0.1088 | -0.4096 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1235 | 332 | 4326 | 0.0767 | -0.5165 |
| MCF7 | Radicicol | 0.04 | uM | LJP6 | 1 | K12 | 72 | hr | 1235 | 2599 | 3974 | 0.6540 | 0.5546 |
| MCF7 | Radicicol | 0.04 | uM | LJP6 | 2 | K12 | 72 | hr | 1235 | 2454 | 4070 | 0.6029 | 0.4903 |