LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 1 | J01 | 72 | hr | 1235 | 380 | 3974 | 0.0956 | -0.5031 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 2 | J01 | 72 | hr | 1235 | 319 | 4070 | 0.0784 | -0.5448 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 3 | J01 | 72 | hr | 1235 | 444 | 4126 | 0.1076 | -0.4446 |
| MCF7 | Pelitinib | 0.04 | uM | LJP5 | 1 | I18 | 72 | hr | 1235 | 4492 | 4119 | 1.0905 | 1.1023 |
| MCF7 | Pelitinib | 0.04 | uM | LJP5 | 2 | I18 | 72 | hr | 1235 | 4733 | 4356 | 1.0865 | 1.0933 |
| MCF7 | Pelitinib | 0.04 | uM | LJP5 | 3 | I18 | 72 | hr | 1235 | 5043 | 4326 | 1.1656 | 1.1769 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 1 | I17 | 72 | hr | 1235 | 4670 | 4119 | 1.1337 | 1.1498 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 2 | I17 | 72 | hr | 1235 | 4703 | 4356 | 1.0796 | 1.0860 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 3 | I17 | 72 | hr | 1235 | 5374 | 4326 | 1.2421 | 1.2548 |
| MCF7 | Pelitinib | 0.37 | uM | LJP5 | 1 | I16 | 72 | hr | 1235 | 3845 | 4119 | 0.9334 | 0.9223 |
| MCF7 | Pelitinib | 0.37 | uM | LJP5 | 2 | I16 | 72 | hr | 1235 | 4679 | 4356 | 1.0741 | 1.0802 |
| MCF7 | Pelitinib | 0.37 | uM | LJP5 | 3 | I16 | 72 | hr | 1235 | 4468 | 4326 | 1.0327 | 1.0359 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 1 | I15 | 72 | hr | 1235 | 3592 | 4119 | 0.8720 | 0.8484 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 2 | I15 | 72 | hr | 1235 | 3818 | 4356 | 0.8764 | 0.8601 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 3 | I15 | 72 | hr | 1235 | 3710 | 4326 | 0.8575 | 0.8370 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 1 | I14 | 72 | hr | 1235 | 1852 | 4119 | 0.4496 | 0.2624 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 2 | I14 | 72 | hr | 1235 | 2022 | 4356 | 0.4642 | 0.3113 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 3 | I14 | 72 | hr | 1235 | 1940 | 4326 | 0.4484 | 0.2835 |
| MCF7 | Pelitinib | 10 | uM | LJP5 | 1 | I13 | 72 | hr | 1235 | 1224 | 4119 | 0.2971 | -0.0053 |
| MCF7 | Pelitinib | 10 | uM | LJP5 | 2 | I13 | 72 | hr | 1235 | 944 | 4356 | 0.2167 | -0.1375 |
| MCF7 | Pelitinib | 10 | uM | LJP5 | 3 | I13 | 72 | hr | 1235 | 1079 | 4326 | 0.2494 | -0.0721 |
| MCF7 | Luminespib | 0.04 | uM | LJP5 | 1 | H18 | 72 | hr | 1235 | 1399 | 4119 | 0.3396 | 0.0742 |
| MCF7 | Luminespib | 0.04 | uM | LJP5 | 2 | H18 | 72 | hr | 1235 | 1522 | 4356 | 0.3494 | 0.1216 |
| MCF7 | Luminespib | 0.04 | uM | LJP5 | 3 | H18 | 72 | hr | 1235 | 1436 | 4326 | 0.3319 | 0.0868 |
| MCF7 | Luminespib | 0.12 | uM | LJP5 | 1 | H17 | 72 | hr | 1235 | 1348 | 4119 | 0.3273 | 0.0515 |