LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 1235 3805 3974 0.9574 0.9491
MCF7 Saracatinib
0.04
uM
LJP6
 2
D12
 72
hr
 1235 4039 4070 0.9923 0.9910
MCF7 Saracatinib
0.04
uM
LJP6
 3
D12
 72
hr
 1235 3458 4126 0.8380 0.8069
MCF7 Saracatinib
0.12
uM
LJP6
 1
D11
 72
hr
 1235 2918 3974 0.7343 0.6651
MCF7 Saracatinib
0.12
uM
LJP6
 2
D11
 72
hr
 1235 3172 4070 0.7793 0.7301
MCF7 Saracatinib
0.12
uM
LJP6
 3
D11
 72
hr
 1235 2482 4126 0.6015 0.4933
MCF7 Saracatinib
0.37
uM
LJP6
 1
D10
 72
hr
 1235 2209 3974 0.5558 0.4117
MCF7 Saracatinib
0.37
uM
LJP6
 2
D10
 72
hr
 1235 1885 4070 0.4631 0.2784
MCF7 Saracatinib
0.37
uM
LJP6
 3
D10
 72
hr
 1235 1947 4126 0.4718 0.2988
MCF7 Saracatinib
1.11
uM
LJP6
 1
D09
 72
hr
 1235 1555 3974 0.3913 0.1463
MCF7 Saracatinib
1.11
uM
LJP6
 2
D09
 72
hr
 1235 1917 4070 0.4710 0.2910
MCF7 Saracatinib
1.11
uM
LJP6
 3
D09
 72
hr
 1235 1592 4126 0.3858 0.1569
MCF7 Saracatinib
3.33
uM
LJP6
 1
D08
 72
hr
 1235 1443 3974 0.3631 0.0965
MCF7 Saracatinib
3.33
uM
LJP6
 2
D08
 72
hr
 1235 1542 4070 0.3788 0.1376
MCF7 Saracatinib
3.33
uM
LJP6
 3
D08
 72
hr
 1235 1521 4126 0.3686 0.1270
MCF7 Saracatinib
10
uM
LJP6
 1
D07
 72
hr
 1235 1562 3974 0.3930 0.1493
MCF7 Saracatinib
10
uM
LJP6
 2
D07
 72
hr
 1235 1922 4070 0.4722 0.2930
MCF7 Saracatinib
10
uM
LJP6
 3
D07
 72
hr
 1235 1626 4126 0.3941 0.1711
MCF7 Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 1235 2961 4119 0.7188 0.6539
MCF7 Sigma A6730
0.04
uM
LJP5
 2
B24
 72
hr
 1235 3319 4356 0.7619 0.7221
MCF7 Sigma A6730
0.04
uM
LJP5
 3
B24
 72
hr
 1235 3712 4326 0.8580 0.8376
MCF7 Sigma A6730
0.12
uM
LJP5
 1
B23
 72
hr
 1235 3183 4119 0.7727 0.7242
MCF7 Sigma A6730
0.12
uM
LJP5
 2
B23
 72
hr
 1235 3222 4356 0.7396 0.6943
MCF7 Sigma A6730
0.12
uM
LJP5
 3
B23
 72
hr
 1235 3240 4326 0.7489 0.7044
MCF7 Sigma A6730
0.37
uM
LJP5
 1
B22
 72
hr
 1235 3213 4119 0.7800 0.7335