LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HG-6-64-01 | 0.04 | uM | LJP6 | 3 | M06 | 72 | hr | 1235 | 5015 | 4126 | 1.2154 | 1.2372 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 1 | M05 | 72 | hr | 1235 | 4555 | 3974 | 1.1462 | 1.1686 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 2 | M05 | 72 | hr | 1235 | 4533 | 4070 | 1.1137 | 1.1292 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 3 | M05 | 72 | hr | 1235 | 4753 | 4126 | 1.1519 | 1.1693 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 1 | M04 | 72 | hr | 1235 | 4395 | 3974 | 1.1059 | 1.1231 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 2 | M04 | 72 | hr | 1235 | 3817 | 4070 | 0.9378 | 0.9267 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 3 | M04 | 72 | hr | 1235 | 3757 | 4126 | 0.9105 | 0.8951 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 1 | M03 | 72 | hr | 1235 | 3663 | 3974 | 0.9217 | 0.9056 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 2 | M03 | 72 | hr | 1235 | 3376 | 4070 | 0.8294 | 0.7939 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 3 | M03 | 72 | hr | 1235 | 3259 | 4126 | 0.7898 | 0.7463 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 1 | M02 | 72 | hr | 1235 | 2674 | 3974 | 0.6729 | 0.5811 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 2 | M02 | 72 | hr | 1235 | 2470 | 4070 | 0.6068 | 0.4960 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 3 | M02 | 72 | hr | 1235 | 2614 | 4126 | 0.6335 | 0.5384 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 1 | M01 | 72 | hr | 1235 | 814 | 3974 | 0.2048 | -0.2192 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 1235 | 661 | 4070 | 0.1624 | -0.3048 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 3 | M01 | 72 | hr | 1235 | 630 | 4126 | 0.1527 | -0.3209 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 1 | A18 | 72 | hr | 1235 | 3027 | 4119 | 0.7349 | 0.6750 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 2 | A18 | 72 | hr | 1235 | 3202 | 4356 | 0.7350 | 0.6885 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 3 | A18 | 72 | hr | 1235 | 3393 | 4326 | 0.7843 | 0.7485 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 1 | A17 | 72 | hr | 1235 | 2692 | 4119 | 0.6535 | 0.5657 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 2 | A17 | 72 | hr | 1235 | 2993 | 4356 | 0.6871 | 0.6269 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 3 | A17 | 72 | hr | 1235 | 2807 | 4326 | 0.6488 | 0.5744 |
| MCF7 | Neratinib | 0.37 | uM | LJP5 | 1 | A16 | 72 | hr | 1235 | 2722 | 4119 | 0.6608 | 0.5757 |
| MCF7 | Neratinib | 0.37 | uM | LJP5 | 2 | A16 | 72 | hr | 1235 | 2818 | 4356 | 0.6469 | 0.5739 |
| MCF7 | Neratinib | 0.37 | uM | LJP5 | 3 | A16 | 72 | hr | 1235 | 2527 | 4326 | 0.5841 | 0.4855 |