LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 JW-7-24-1
0.12
uM
LJP6
 72
hr
 1097 3059 3769 0.8115 0.7341
BT-20 Lapatinib
0.12
uM
LJP6
 72
hr
 1097 3280 3769 0.8703 0.8171
BT-20 LDN-193189
0.12
uM
LJP5
 72
hr
 1097 3388 3769 0.8989 0.8574
BT-20 Linifanib
0.12
uM
LJP6
 72
hr
 1097 3763 3769 0.9983 0.9976
BT-20 Linsitinib
0.12
uM
LJP5
 72
hr
 1097 3616 3769 0.9593 0.9425
BT-20 Mitoxantrone
0.12
uM
LJP5
 72
hr
 1097 1136 3769 0.3014 0.0145
BT-20 Mitoxantrone
0.12
uM
LJP6
 72
hr
 1097 1149 3769 0.3050 0.0196
BT-20 MK2206
0.12
uM
LJP6
 72
hr
 1097 2986 3769 0.7923 0.7070
BT-20 Neratinib
0.12
uM
LJP5
 72
hr
 1097 2626 3769 0.6968 0.5723
BT-20 Nilotinib
0.12
uM
LJP5
 72
hr
 1097 4002 3769 1.0618 1.0872
BT-20 Nintedanib
0.12
uM
LJP6
 72
hr
 1097 3389 3769 0.8992 0.8579
BT-20 NU7441
0.12
uM
LJP5
 72
hr
 1097 3754 3769 0.9959 0.9942
BT-20 Dactolisib
0.12
uM
LJP5
 72
hr
 1097 1098 3769 0.2913 0.0003
BT-20 NVP-TAE684
0.12
uM
LJP6
 72
hr
 1097 3679 3769 0.9762 0.9664
BT-20 Palbociclib
0.12
uM
LJP6
 72
hr
 1097 1959 3769 0.5197 0.3225
BT-20 PD0325901
0.12
uM
LJP5
 72
hr
 1097 3094 3769 0.8209 0.7473
BT-20 PD0325901
0.12
uM
LJP6
 72
hr
 1097 3152 3769 0.8363 0.7690
BT-20 PD173074
0.12
uM
LJP6
 72
hr
 1097 3999 3769 1.0609 1.0859
BT-20 PD184352
0.12
uM
LJP5
 72
hr
 1097 3927 3769 1.0419 1.0592
BT-20 Pelitinib
0.12
uM
LJP5
 72
hr
 1097 3065 3769 0.8132 0.7365
BT-20 PF431396
0.12
uM
LJP5
 72
hr
 1097 2975 3769 0.7894 0.7029
BT-20 PF477736
0.12
uM
LJP5
 72
hr
 1097 3621 3769 0.9606 0.9444
BT-20 PF562271
0.12
uM
LJP6
 72
hr
 1097 3400 3769 0.9021 0.8620
BT-20 PHA-665752
0.12
uM
LJP5
 72
hr
 1097 3713 3769 0.9852 0.9791
BT-20 PHA-793887
0.12
uM
LJP6
 72
hr
 1097 2010 3769 0.5333 0.3417