LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A PI103
3.33
uM
LJP6
 72
hr
 962 1349 10605 0.1273 0.0402
MCF 10A PLX-4720
3.33
uM
LJP5
 72
hr
 962 9312 10605 0.8781 0.8659
MCF 10A QL-X-138
3.33
uM
LJP6
 72
hr
 962 2805 10605 0.2645 0.1911
MCF 10A QL-XII-47
3.33
uM
LJP6
 72
hr
 962 3256 10605 0.3071 0.2379
MCF 10A Radicicol
3.33
uM
LJP5
 72
hr
 962 760 10605 0.0717 -0.0209
MCF 10A Radicicol
3.33
uM
LJP6
 72
hr
 962 758 10605 0.0715 -0.0212
MCF 10A Seliciclib
3.33
uM
LJP5
 72
hr
 962 8937 10605 0.8427 0.8270
MCF 10A Ruxolitinib
3.33
uM
LJP5
 72
hr
 962 9673 10605 0.9122 0.9034
MCF 10A XL147
3.33
uM
LJP5
 72
hr
 962 7621 10605 0.7186 0.6905
MCF 10A Saracatinib
3.33
uM
LJP6
 72
hr
 962 5442 10605 0.5132 0.4646
MCF 10A Selumetinib
3.33
uM
LJP6
 72
hr
 962 2226 10605 0.2099 0.1311
MCF 10A Sirolimus
3.33
uM
LJP6
 72
hr
 962 9200 10605 0.8676 0.8544
MCF 10A Sorafenib
3.33
uM
LJP6
 72
hr
 962 9121 10605 0.8601 0.8461
MCF 10A SU11274
3.33
uM
LJP5
 72
hr
 962 6858 10605 0.6467 0.6115
MCF 10A Fedratinib
3.33
uM
LJP5
 72
hr
 962 4226 10605 0.3985 0.3385
MCF 10A TGX221
3.33
uM
LJP5
 72
hr
 962 10595 10605 0.9991 0.9990
MCF 10A Torin1
3.33
uM
LJP6
 72
hr
 962 1594 10605 0.1503 0.0655
MCF 10A Torin2
3.33
uM
LJP5
 72
hr
 962 1380 10605 0.1302 0.0434
MCF 10A Tozasertib
3.33
uM
LJP5
 72
hr
 962 1348 10605 0.1272 0.0401
MCF 10A Trametinib
3.33
uM
LJP5
 72
hr
 962 1925 10605 0.1815 0.0998
MCF 10A TWS119
3.33
uM
LJP5
 72
hr
 962 9675 10605 0.9123 0.9036
MCF 10A Vemurafenib
3.33
uM
LJP5
 72
hr
 962 8735 10605 0.8237 0.8061
MCF 10A Withaferin A
3.33
uM
LJP5
 72
hr
 962 685 10605 0.0647 -0.0287
MCF 10A Withaferin A
3.33
uM
LJP6
 72
hr
 962 599 10605 0.0565 -0.0376
MCF 10A WYE-125132
3.33
uM
LJP6
 72
hr
 962 1417 10605 0.1336 0.0472