LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T AZD-6482
0.37
uM
LJP5
 72
hr
 658 3419 3846 0.8890 0.8661
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 658 632 3846 0.1645 -0.0080
Hs 578T AZD8055
0.37
uM
LJP6
 72
hr
 658 939 3846 0.2442 0.0882
Hs 578T AZD8330
0.37
uM
LJP5
 72
hr
 658 989 3846 0.2572 0.1039
Hs 578T Barasertib
0.37
uM
LJP5
 72
hr
 658 1162 3846 0.3021 0.1580
Hs 578T BI-2536
0.37
uM
LJP6
 72
hr
 658 527 3846 0.1372 -0.0409
Hs 578T BMS345541
0.37
uM
LJP6
 72
hr
 658 3676 3846 0.9559 0.9467
Hs 578T SNS-032
0.37
uM
LJP6
 72
hr
 658 518 3846 0.1348 -0.0439
Hs 578T GDC-0980
0.37
uM
LJP5
 72
hr
 658 1379 3846 0.3587 0.2263
Hs 578T NVP-AEW541
0.37
uM
LJP5
 72
hr
 658 4004 3846 1.0412 1.0497
Hs 578T SB590885
0.37
uM
LJP5
 72
hr
 658 4046 3846 1.0521 1.0628
Hs 578T PIK-93
0.37
uM
LJP5
 72
hr
 658 3600 3846 0.9361 0.9229
Hs 578T KIN001-043
0.37
uM
LJP6
 72
hr
 658 3888 3846 1.0111 1.0133
Hs 578T Alpelisib
0.37
uM
LJP5
 72
hr
 658 3351 3846 0.8714 0.8449
Hs 578T Luminespib
0.37
uM
LJP5
 72
hr
 658 769 3846 0.2000 0.0349
Hs 578T A443654
0.37
uM
LJP6
 72
hr
 658 384 3846 0.0998 -0.0860
Hs 578T OSI-027
0.37
uM
LJP6
 72
hr
 658 2734 3846 0.7110 0.6514
Hs 578T XMD11-85h
0.37
uM
LJP6
 72
hr
 658 3316 3846 0.8622 0.8337
Hs 578T HG-6-64-01
0.37
uM
LJP6
 72
hr
 658 1542 3846 0.4010 0.2773
Hs 578T WH-4-025
0.37
uM
LJP5
 72
hr
 658 1173 3846 0.3050 0.1615
Hs 578T WZ-4-145
0.37
uM
LJP6
 72
hr
 658 2117 3846 0.5504 0.4576
Hs 578T XMD16-144
0.37
uM
LJP5
 72
hr
 658 778 3846 0.2023 0.0376
Hs 578T Brivanib
0.37
uM
LJP5
 72
hr
 658 3736 3846 0.9714 0.9655
Hs 578T Buparlisib
0.37
uM
LJP5
 72
hr
 658 2458 3846 0.6392 0.5647
Hs 578T BX-912
0.37
uM
LJP5
 72
hr
 658 2112 3846 0.5492 0.4561