LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP5 | 72 | hr | 1235 | 86 | 4513 | 0.0191 | -0.3507 |
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP6 | 72 | hr | 1235 | 108 | 4513 | 0.0241 | -0.3439 |
| MDA-MB-231 | MK2206 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1856 | 4513 | 0.4112 | 0.1892 |
| MDA-MB-231 | Neratinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 797 | 4513 | 0.1767 | -0.1337 |
| MDA-MB-231 | Nilotinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1004 | 4513 | 0.2226 | -0.0706 |
| MDA-MB-231 | Nintedanib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1099 | 4513 | 0.2436 | -0.0416 |
| MDA-MB-231 | NU7441 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1195 | 4513 | 0.2649 | -0.0123 |
| MDA-MB-231 | Dactolisib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1645 | 4513 | 0.3645 | 0.1249 |
| MDA-MB-231 | NVP-TAE684 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 382 | 4513 | 0.0848 | -0.2603 |
| MDA-MB-231 | Palbociclib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1812 | 4513 | 0.4016 | 0.1760 |
| MDA-MB-231 | PD0325901 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 835 | 4513 | 0.1851 | -0.1221 |
| MDA-MB-231 | PD0325901 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 641 | 4513 | 0.1422 | -0.1813 |
| MDA-MB-231 | PD173074 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1624 | 4513 | 0.3599 | 0.1185 |
| MDA-MB-231 | PD184352 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1449 | 4513 | 0.3211 | 0.0651 |
| MDA-MB-231 | Pelitinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 756 | 4513 | 0.1676 | -0.1463 |
| MDA-MB-231 | PF431396 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 433 | 4513 | 0.0959 | -0.2450 |
| MDA-MB-231 | PF477736 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 888 | 4513 | 0.1968 | -0.1061 |
| MDA-MB-231 | PF562271 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 460 | 4513 | 0.1021 | -0.2365 |
| MDA-MB-231 | PHA-665752 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 131 | 4513 | 0.0291 | -0.3370 |
| MDA-MB-231 | PHA-793887 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 398 | 4513 | 0.0883 | -0.2556 |
| MDA-MB-231 | PI103 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1139 | 4513 | 0.2524 | -0.0296 |
| MDA-MB-231 | PLX-4720 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 3832 | 4513 | 0.8491 | 0.7921 |
| MDA-MB-231 | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 760 | 4513 | 0.1685 | -0.1451 |
| MDA-MB-231 | QL-XII-47 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 717 | 4513 | 0.1590 | -0.1581 |
| MDA-MB-231 | Radicicol | 10.0 | uM | LJP5 | 72 | hr | 1235 | 971 | 4513 | 0.2153 | -0.0806 |