LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1401 | 2267 | 4223 | 0.5370 | 0.3070 |
| SK-BR-3 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4041 | 4223 | 0.9570 | 0.9356 |
| SK-BR-3 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3487 | 4223 | 0.8259 | 0.7394 |
| SK-BR-3 | Imatinib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4559 | 4223 | 1.0795 | 1.1191 |
| SK-BR-3 | JNK-9L | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3440 | 4223 | 0.8147 | 0.7226 |
| SK-BR-3 | JW-7-24-1 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3356 | 4223 | 0.7947 | 0.6927 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1499 | 4223 | 0.3551 | 0.0348 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4081 | 4223 | 0.9664 | 0.9498 |
| SK-BR-3 | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4479 | 4223 | 1.0608 | 1.0909 |
| SK-BR-3 | Linsitinib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3872 | 4223 | 0.9169 | 0.8756 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1514 | 4223 | 0.3587 | 0.0401 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1434 | 4223 | 0.3397 | 0.0117 |
| SK-BR-3 | MK2206 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 2820 | 4223 | 0.6678 | 0.5028 |
| SK-BR-3 | Neratinib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1511 | 4223 | 0.3579 | 0.0389 |
| SK-BR-3 | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4727 | 4223 | 1.1194 | 1.1787 |
| SK-BR-3 | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4054 | 4223 | 0.9601 | 0.9403 |
| SK-BR-3 | NU7441 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3973 | 4223 | 0.9409 | 0.9116 |
| SK-BR-3 | Dactolisib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1559 | 4223 | 0.3693 | 0.0560 |
| SK-BR-3 | NVP-TAE684 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4201 | 4223 | 0.9949 | 0.9923 |
| SK-BR-3 | Palbociclib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3081 | 4223 | 0.7296 | 0.5954 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3932 | 4223 | 0.9311 | 0.8968 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3773 | 4223 | 0.8936 | 0.8407 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4239 | 4223 | 1.0038 | 1.0058 |
| SK-BR-3 | PD184352 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4570 | 4223 | 1.0822 | 1.1231 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1671 | 4223 | 0.3958 | 0.0956 |