LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Selumetinib
10.0
uM
LJP6
 72
hr
 962 1692 10605 0.1596 0.0758
MCF 10A Sirolimus
10.0
uM
LJP6
 72
hr
 962 9031 10605 0.8516 0.8368
MCF 10A Sorafenib
10.0
uM
LJP6
 72
hr
 962 4414 10605 0.4163 0.3580
MCF 10A SU11274
10.0
uM
LJP5
 72
hr
 962 3529 10605 0.3328 0.2662
MCF 10A Fedratinib
10.0
uM
LJP5
 72
hr
 962 1123 10605 0.1059 0.0167
MCF 10A TGX221
10.0
uM
LJP5
 72
hr
 962 10603 10605 0.9998 0.9998
MCF 10A Torin1
10.0
uM
LJP6
 72
hr
 962 1262 10605 0.1190 0.0311
MCF 10A Torin2
10.0
uM
LJP5
 72
hr
 962 1277 10605 0.1204 0.0327
MCF 10A Tozasertib
10.0
uM
LJP5
 72
hr
 962 1266 10605 0.1194 0.0316
MCF 10A Trametinib
10.0
uM
LJP5
 72
hr
 962 1979 10605 0.1866 0.1055
MCF 10A TWS119
10.0
uM
LJP5
 72
hr
 962 1247 10605 0.1176 0.0296
MCF 10A Vemurafenib
10.0
uM
LJP5
 72
hr
 962 4165 10605 0.3928 0.3322
MCF 10A Withaferin A
10.0
uM
LJP5
 72
hr
 962 594 10605 0.0561 -0.0381
MCF 10A Withaferin A
10.0
uM
LJP6
 72
hr
 962 574 10605 0.0541 -0.0403
MCF 10A WYE-125132
10.0
uM
LJP6
 72
hr
 962 1427 10605 0.1346 0.0482
MCF 10A WZ3105
10.0
uM
LJP5
 72
hr
 962 185 10605 0.0175 -0.0806
MCF 10A XMD11-50
10.0
uM
LJP6
 72
hr
 962 1194 10605 0.1127 0.0241
MCF 10A Y39983
10.0
uM
LJP6
 72
hr
 962 4273 10605 0.4030 0.3434
MCF 10A YM 201636
10.0
uM
LJP5
 72
hr
 962 2670 10605 0.2518 0.1771
MCF 10A ZSTK474
10.0
uM
LJP6
 72
hr
 962 1349 10605 0.1273 0.0402
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1209 3665 4093 0.8955 0.8517
MCF7 Sigma A6730
0.04
uM
LJP5
 72
hr
 1209 3392 4093 0.8287 0.7569
MCF7 Alvocidib
0.04
uM
LJP6
 72
hr
 1209 673 4093 0.1646 -0.1859
MCF7 AT-7519
0.04
uM
LJP6
 72
hr
 1209 1716 4093 0.4193 0.1756
MCF7 AZD 5438
0.04
uM
LJP6
 72
hr
 1209 2897 4093 0.7079 0.5853